SCHEMBL27193602

SCHEMBL27193602

C=Cc1cccc([Si](CCCCCCCCCCCC)(c2cccc(C=C)c2)c2cccc(C=C)c2)c1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.41
TP53 P04637 1/20 0.41
KCNH2 Q12809 2/20 0.39
GPR84 Q9NQS5 1/20 0.34
EGFR P00533 1/20 0.33
TSHR P16473 2/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.31
POLB P06746 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
STS P08842 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CNR1 P21554 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL713836 0.86 TDP1 (0.40) TDP1TP53KCNH2GPR84EGFR
SCHEMBL27193610 0.84 KCNH2 (0.39) TDP1KCNH2GPR84EGFRALDH1A1
SCHEMBL27193608 0.80 ALDH1A1 (0.39) KCNH2GPR84TSHRALDH1A1CA1
SCHEMBL611131 0.77 TP53 (0.40) TDP1TP53KCNH2TSHRALDH1A1
SCHEMBL29515041 0.77 TP53 (0.40) TDP1TP53KCNH2TSHRALDH1A1
SCHEMBL2454227 0.77 KCNH2 (0.43) TP53KCNH2GPR84ALDH1A1CNR1
SCHEMBL1270702 0.76 TP53 (0.34) TDP1TP53TSHRALDH1A1
SCHEMBL21829873 0.76 TP53 (0.39) TDP1TP53TSHR
SCHEMBL23532346 0.76 KCNH2 (0.42) KCNH2GPR84
SCHEMBL23532424 0.76 EPHX1 (0.46) KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240117152-A1 NOVEL ORGANOSILICON COMPOUND, NOVEL CROSSLINKING AGENT, CURABLE COMPOSITION, PREPREG, MULTILAYER BODY, METAL CLAD LAMINATE AND WIRING BOARD AGC Inc. (JP) 2024-04-11 US disclosed