SCHEMBL1270702

SCHEMBL1270702

C=Cc1cccc([Si](CCC[Si](OCC)(OCC)OCC)(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ALDH1A1 P00352 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9067720 0.88
SCHEMBL27193602 0.76 TDP1 (0.41) TP53TDP1ALDH1A1TSHR
SCHEMBL9316455 0.75 TLR4 (0.42) TP53TDP1ALDH1A1TSHR
SCHEMBL29434674 0.74 TP53 (0.44) TP53TDP1ALDH1A1TSHR
SCHEMBL437296 0.74 TP53 (0.44) TP53TDP1ALDH1A1TSHR
SCHEMBL23493464 0.73 TP53 (0.43) TP53TDP1ALDH1A1TSHR
SCHEMBL29434597 0.73 TP53 (0.43) TP53TDP1ALDH1A1TSHR
SCHEMBL21247626 0.72 TP53 (0.40) TP53TDP1ALDH1A1TSHR
Styrene SCHEMBL28326763 0.72 TSHR (0.39) ALDH1A1TSHR
SCHEMBL31468627 0.72 TP53 (0.34) TP53TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0367219-B1 Polyorganosiloxane series thermoplastic resin and composition thereof JAPAN SYNTHETIC RUBBER CO LTD (JP) 1994-08-31 EP claimed
US-5147947-A Graft polymer containing vinyl monomer; friction resistance JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1992-09-15 US claimed
EP-0367219-A2 Polyorganosiloxane series thermoplastic resin and composition thereof JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1990-05-09 EP claimed
US-20250019536-A1 STRESS REDUCING AGENT AND RESIN COMPOSITION KANEKA CORPORATION (JP) 2025-01-16 US disclosed
EP-4446352-A1 WATER-BASED COATING Kaneka Corporation (JP) 2024-10-16 EP disclosed
US-20240327671-A1 WATER-BASED COATING KANEKA CORPORATION (JP) 2024-10-03 US disclosed
CN-118369388-A Water paint 株式会社钟化 2024-07-19 CN disclosed
US-20130037098-A1 INFRARED REFLECTIVE LAMINATE TECHNO POLYMER CO., LTD (JP) 2013-02-14 US disclosed
US-8339700-B2 Infrared reflective laminate TECHNO POLYMER CO., LTD (JP) 2012-12-25 US disclosed
US-20110284071-A1 MULTILAYER BODY Techno- Polymer Co., Ltd. (JP) 2011-11-24 US disclosed
US-20110061720-A1 LAMINATE TECHNO POLYMER CO., LTD. (JP) 2011-03-17 US disclosed
EP-0653447-A1 Polyorganosiloxane-type thermoplastic resin JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1995-05-17 EP disclosed
EP-0367219-B1 Polyorganosiloxane series thermoplastic resin and composition thereof JAPAN SYNTHETIC RUBBER CO LTD (JP) 1994-08-31 EP disclosed
EP-0578873-A1 Flame-retardant resin composition DSM N.V. (NL) 1994-01-19 EP disclosed
US-5250615-A Slidability; abrasion, weather, cold and impact resistance JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1993-10-05 US disclosed
US-5218014-A Graft polymer formed by graft polymerization of vinyl monomer onto colloidal silica core silicone shell particles TOSHIBA SILICONE CO., LTD. (JP) 1993-06-08 US disclosed
US-5188899-A SILICA-CORE SILICONE-SHELL PARTICLES, EMULSION CONTAINING THE SAME DISPERSED THEREIN, AND PROCESS FOR PRODUCING THE EMULSION TOSHIBA SILICONE CO., LTD. (JP) 1993-02-23 US disclosed
US-5147947-A Graft polymer containing vinyl monomer; friction resistance JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1992-09-15 US disclosed
EP-0433906-A2 Thermoplastic resin and process for producing the same TOSHIBA SILICONE CO., LTD. (JP) 1991-06-26 EP disclosed
EP-0433727-A1 Silica-core silicone-shell particles, emulsion containing the same dispersed therein, and process for producing the emulsion TOSHIBA SILICONE CO., LTD. (JP) 1991-06-26 EP disclosed