Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 4/20 | 0.87 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.87 |
| ▸ | CA12 | O43570 | 2/20 | 0.87 |
| ▸ | CA2 | P00918 | 2/20 | 0.87 |
| ▸ | CA4 | P22748 | 2/20 | 0.87 |
| ▸ | CA7 | P43166 | 2/20 | 0.87 |
| ▸ | ACHE | P22303 | 1/20 | 0.87 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.76 |
| ▸ | GAA | P10253 | 4/20 | 0.76 |
| ▸ | POLB | P06746 | 3/20 | 0.76 |
| ▸ | APEX1 | P27695 | 1/20 | 0.76 |
| ▸ | RECQL | P46063 | 1/20 | 0.76 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.75 |
| ▸ | MAPT | P10636 | 2/20 | 0.75 |
| ▸ | SLCO2B1 | O94956 | 2/20 | 0.75 |
| ▸ | LMNA | P02545 | 2/20 | 0.75 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.75 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.75 |
| ▸ | KDM1A | O60341 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30217565 | 1.00 | P4HB (0.87) | P4HBAKR1B1CA12CA2CA4 | |
| SCHEMBL9993788 | 1.00 | P4HB (0.87) | P4HBAKR1B1CA12CA2CA4 | |
| SCHEMBL29453024 | 1.00 | P4HB (0.87) | P4HBAKR1B1CA12CA2CA4 | |
| SCHEMBL4391457 | 1.00 | P4HB (0.87) | P4HBAKR1B1CA12CA2CA4 | |
| SCHEMBL31173775 | 1.00 | P4HB (0.87) | P4HBAKR1B1CA12CA2CA4 | |
| SCHEMBL30456667 | 0.95 | P4HB (0.79) | P4HBAKR1B1CA12CA2CA4 | |
| SCHEMBL9993267 | 0.95 | P4HB (0.79) | P4HBAKR1B1CA12CA2CA4 | |
| SCHEMBL30217549 | 0.95 | P4HB (0.79) | P4HBAKR1B1CA12CA2CA4 | |
| SCHEMBL30637576 | 0.95 | P4HB (0.79) | P4HBAKR1B1CA12CA2CA4 | |
| SCHEMBL31720497 | 0.95 | P4HB (0.79) | P4HBAKR1B1CA12CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240115645-A1 | DRUG FOR TREATING UROLITHIASIS-RELATED DISEASE, AND PREPARATION METHOD THEREFOR | HONG ZHANG (CN) | 2024-04-11 | — | — | US | disclosed |
| CN-117582464-A | Extraction method and application of active ingredients for treating cerebral infarction in Va drug Nie Liang administration | 云南省中医医院(云南中医药大学第一附属医院) | 2024-02-23 | — | — | CN | disclosed |
| CN-115212252-A | Application of Va drug Nierone in preparation of drugs for treating cerebral infarction | 云南省中医医院(云南中医药大学第一附属医院) | 2022-10-21 | — | — | CN | disclosed |
| CN-114031656-A | Medicine for treating urinary calculus related diseases and preparation method thereof | 张弘 | 2022-02-11 | — | — | CN | disclosed |
| CN-113559198-A | Medicine special for treating lumbar disc herniation | 杨守信 | 2021-10-29 | — | — | CN | disclosed |
| CN-113521194-A | Medicinal liquor and preparation method and application thereof | 谢小来 | 2021-10-22 | — | — | CN | disclosed |
| CN-109490437-B | Fingerprint detection method of white peony root | 南京海昌中药集团有限公司 | 2021-05-25 | — | — | CN | disclosed |
| CN-112717010-A | Traditional Chinese medicine composition for treating wind-cold exterior deficiency syndrome of new coronavirus and preparation method thereof | 徐修信 | 2021-04-30 | — | — | CN | disclosed |
| CN-108948125-B | Method for preparing polygala japonica sapogenin by using polygala japonica | 长沙爱扬医药科技有限公司 | 2021-01-26 | — | — | CN | disclosed |
| CN-110613833-A | Mucosa repair composition | 上海龙禧投资有限公司 | 2019-12-27 | — | — | CN | disclosed |
| CN-109490437-A | The fingerprint atlas detection method of Radix Paeoniae Alba | 南京海昌中药集团有限公司 | 2019-03-19 | — | — | CN | disclosed |
| CN-108948125-A | The method for preparing Japanese polygala saponin member using Japanese polygala | 长沙爱扬医药科技有限公司 | 2018-12-07 | — | — | CN | disclosed |
| CN-104873733-B | A kind of functional pharmaceutical chemistry inhibiting female soft-shelled turtle gonad development and preparation method thereof and feeding method | 合肥市畜牧水产技术推广中心 | 2018-07-24 | — | — | CN | disclosed |
| CN-105596974-A | White peony root health oral liquid for invigorating energy, tonifying blood and removing spots, and preparation method thereof | QINGDAO HENGBO INSTR CO LTD | 2016-05-25 | — | — | CN | disclosed |
| CN-1305415-C | Sports type health-care beverage and preparation method thereof | SHAO JIANGUO (CN) | 2007-03-21 | — | — | CN | disclosed |
| CN-1666675-A | Sports type health-care beverage and preparation method thereof | SHAO JIANGUO (CN) | 2005-09-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240115645-A1 | DRUG FOR TREATING UROLITHIASIS-RELATED DISEASE, AND PREPARATION METHOD THEREFOR | HK1, HKDC1, HK2 | P4HB 3720/4885AKR1B1 2067/4885CA12 2601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.