Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 7/20 | 0.36 |
| ▸ | P2RY6 | Q15077 | 4/20 | 0.36 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.33 |
| ▸ | TRPM2 | O94759 | 2/20 | 0.32 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL272356 | 0.93 | P2RY2 (0.42) | P2RY2P2RY6P2RY4P2RX3P2RX2 | |
| SCHEMBL271983 | 0.89 | P2RY2 (0.36) | P2RY2P2RY6P2RY4ALDH1A1P2RX3 | |
| SCHEMBL272498 | 0.87 | P2RY2 (0.36) | P2RY2P2RY6P2RY4ALDH1A1P2RY14 | |
| SCHEMBL271898 | 0.77 | P2RY2 (0.32) | P2RY2P2RY6P2RY4 | |
| SCHEMBL271982 | 0.77 | P2RY2 (0.39) | P2RY2P2RY6P2RY4ALDH1A1P2RX3 | |
| SCHEMBL271873 | 0.76 | P2RY2 (0.35) | P2RY2P2RY6P2RY4 | |
| SCHEMBL272500 | 0.73 | P2RX3 (0.43) | P2RY2P2RY6P2RY4P2RX3P2RX2 | |
| SCHEMBL17018681 | 0.72 | — | — | |
| SCHEMBL271940 | 0.71 | P2RY2 (0.34) | P2RY2P2RY6P2RY4 | |
| SCHEMBL272676 | 0.71 | ALDH1A1 (0.36) | P2RY2P2RY6P2RY4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8133669-B2 | Chemically modified nucleoside 5′-triphosphates for thermally initiated amplification of nucleic acid | TRILINK BIOTECHNOLOGIES (US) | 2012-03-13 | — | — | US | disclosed |
| US-20100003724-A1 | CHEMICALLY MODIFIED NUCLEOSIDE 5'-TRIPHOSPHATES FOR THERMALLY INITIATED AMPLIFICATION OF NUCLEIC ACID | TriLink Bio Technologies | 2010-01-07 | — | — | US | disclosed |