Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPPL1 | O15357 | 6/20 | 0.43 |
| ▸ | INPP5A | Q14642 | 4/20 | 0.43 |
| ▸ | INPP5B | P32019 | 2/20 | 0.43 |
| ▸ | SRC | P12931 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1354465 | 0.90 | CNR1 (0.41) | INPPL1INPP5AINPP5BSRCKDM4E | |
| SCHEMBL18114067 | 0.88 | INPPL1 (0.43) | INPPL1INPP5AINPP5BSRCKDM4E | |
| SCHEMBL2719413 | 0.87 | MEN1 (0.35) | MEN1KMT2ANPSR1L3MBTL1 | |
| SCHEMBL27859933 | 0.87 | INPPL1 (0.46) | INPPL1INPP5AINPP5BSRCKDM4E | |
| SCHEMBL1354464 | 0.83 | INPPL1 (0.44) | INPPL1INPP5AINPP5BSRCKDM4E | |
| SCHEMBL2717054 | 0.81 | MEN1 (0.43) | SRCKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL5007401 | 0.80 | ALDH1A1 (0.49) | INPPL1INPP5AINPP5BSRCKDM4E | |
| SCHEMBL18114040 | 0.80 | SRC (0.49) | INPPL1INPP5AINPP5BSRCKDM4E | |
| SCHEMBL284461 | 0.80 | INPPL1 (0.52) | INPPL1INPP5AINPP5BSRCKDM4E | |
| SCHEMBL29885636 | 0.80 | INPPL1 (0.52) | INPPL1INPP5AINPP5BSRCKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2446005-A1 | ANTI-WEAR AGENTS WITH A REDUCED NEUROTOXICITY | Nyco SA (FR) | 2012-05-02 | — | — | EP | disclosed |
| WO-2010149690-A1 | ANTI-WEAR AGENTS WITH A REDUCED NEUROTOXICITY | NYCO SA (FR) | 2010-12-29 | — | — | WO | disclosed |