SCHEMBL271956

SCHEMBL271956

BC1CC(OC2CCCC(C)O2)C(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O1

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 15/20 0.33
POLB P06746 1/20 0.33
POLA1 P09884 1/20 0.33
POLD1 P28340 1/20 0.33
P2RY4 P51582 7/20 0.32
GPR17 Q13304 1/20 0.31
P2RX1 P51575 2/20 0.31
P2RX3 P56373 2/20 0.31
ENPP1 P22413 1/20 0.31
P2RY1 P47900 1/20 0.31
P2RY6 Q15077 1/20 0.31
P2RY11 Q96G91 1/20 0.31
P2RX4 Q99571 1/20 0.31
P2RX2 Q9UBL9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18602997 1.00 P2RY2 (0.33) P2RY2POLBPOLA1POLD1P2RY4
SCHEMBL272164 0.94 POLB (0.34) P2RY2POLBPOLA1POLD1P2RY4
SCHEMBL272582 0.85 P2RY2 (0.36) P2RY2POLBPOLA1POLD1P2RY4
SCHEMBL271948 0.84 P2RY2 (0.35) P2RY2POLBPOLA1POLD1P2RY4
SCHEMBL21555520 0.80 P2RY2 (0.37) P2RY2POLBPOLA1POLD1P2RY4
SCHEMBL22002630 0.80 P2RY2 (0.37) P2RY2POLBPOLA1POLD1P2RY4
SCHEMBL21555519 0.80 P2RY2 (0.37) P2RY2POLBPOLA1POLD1P2RY4
SCHEMBL25141885 0.79 P2RY2 (0.37) P2RY2POLBPOLA1POLD1P2RY4
SCHEMBL271833 0.78 P2RY2 (0.37) P2RY2POLBPOLA1POLD1P2RY4
SCHEMBL271945 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8133669-B2 Chemically modified nucleoside 5′-triphosphates for thermally initiated amplification of nucleic acid TRILINK BIOTECHNOLOGIES (US) 2012-03-13 US disclosed
US-8133669-B2 Chemically modified nucleoside 5′-triphosphates for thermally initiated amplification of nucleic acid TRILINK BIOTECHNOLOGIES (US) 2012-03-13 US disclosed
US-20100003724-A1 CHEMICALLY MODIFIED NUCLEOSIDE 5'-TRIPHOSPHATES FOR THERMALLY INITIATED AMPLIFICATION OF NUCLEIC ACID TriLink Bio Technologies 2010-01-07 US disclosed
US-20100003724-A1 CHEMICALLY MODIFIED NUCLEOSIDE 5'-TRIPHOSPHATES FOR THERMALLY INITIATED AMPLIFICATION OF NUCLEIC ACID TriLink Bio Technologies 2010-01-07 US disclosed