SCHEMBL272164

SCHEMBL272164

BC1CC(OC2CCC(C)O2)C(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O1

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.34
POLA1 P09884 1/20 0.34
POLD1 P28340 1/20 0.34
P2RY2 P41231 16/20 0.33
P2RY4 P51582 7/20 0.33
P2RX3 P56373 3/20 0.32
P2RX1 P51575 2/20 0.32
P2RY6 Q15077 2/20 0.32
P2RX2 Q9UBL9 2/20 0.32
ENPP1 P22413 1/20 0.32
P2RY1 P47900 1/20 0.32
P2RY11 Q96G91 1/20 0.32
P2RX4 Q99571 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL271956 0.94 P2RY2 (0.33) POLBPOLA1POLD1P2RY2P2RY4
SCHEMBL18602997 0.94 P2RY2 (0.33) POLBPOLA1POLD1P2RY2P2RY4
SCHEMBL272582 0.83 P2RY2 (0.36) POLBPOLA1POLD1P2RY2P2RY4
SCHEMBL271948 0.82 P2RY2 (0.35) POLBPOLA1POLD1P2RY2P2RY4
SCHEMBL21555520 0.81 P2RY2 (0.37) POLBPOLA1POLD1P2RY2P2RY4
SCHEMBL21555519 0.81 P2RY2 (0.37) POLBPOLA1POLD1P2RY2P2RY4
SCHEMBL22002630 0.81 P2RY2 (0.37) POLBPOLA1POLD1P2RY2P2RY4
SCHEMBL25141885 0.80 P2RY2 (0.37) POLBPOLA1POLD1P2RY2P2RY4
SCHEMBL271833 0.80 P2RY2 (0.37) POLBPOLA1POLD1P2RY2P2RY4
SCHEMBL21506757 0.79 POLB (0.39) POLBPOLA1POLD1P2RY2P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2294076-B1 CHEMICALLY MODIFIED NUCLEOSIDE 5'-TRIPHOSPHATES FOR THERMALLY INITIATED REPLICATION OF NUCLEIC ACID TRILINK BIOTECHNOLOGIES (US) 2017-03-08 EP disclosed
US-8133669-B2 Chemically modified nucleoside 5′-triphosphates for thermally initiated amplification of nucleic acid TRILINK BIOTECHNOLOGIES (US) 2012-03-13 US disclosed
US-8133669-B2 Chemically modified nucleoside 5′-triphosphates for thermally initiated amplification of nucleic acid TRILINK BIOTECHNOLOGIES (US) 2012-03-13 US disclosed
US-20100003724-A1 CHEMICALLY MODIFIED NUCLEOSIDE 5'-TRIPHOSPHATES FOR THERMALLY INITIATED AMPLIFICATION OF NUCLEIC ACID TriLink Bio Technologies 2010-01-07 US disclosed
US-20100003724-A1 CHEMICALLY MODIFIED NUCLEOSIDE 5'-TRIPHOSPHATES FOR THERMALLY INITIATED AMPLIFICATION OF NUCLEIC ACID TriLink Bio Technologies 2010-01-07 US disclosed