SCHEMBL27195692

SCHEMBL27195692

CN(C)CCOc1ccc(C(=O)Nc2ccc(Cl)c3ncccc23)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 0.49
▸ SMN1; SMN2 Q16637 2/20 0.49
▸ KMT2A Q03164 5/20 0.48
▸ POLB P06746 2/20 0.48
▸ CACNA1H O95180 3/20 0.48
▸ CACNA1B Q00975 2/20 0.48
▸ HDAC1 Q13547 1/20 0.47
▸ NPC1 O15118 1/20 0.47
▸ RAB9A P51151 1/20 0.47
▸ PAICS P22234 1/20 0.46
▸ HRH3 Q9Y5N1 1/20 0.45
▸ PDE4D Q08499 1/20 0.45
▸ TMEM97 Q5BJF2 1/20 0.44
▸ SIGMAR1 Q99720 1/20 0.44
▸ MEN1 O00255 3/20 0.44
▸ L3MBTL1 Q9Y468 2/20 0.44
▸ PABPC1 P11940 1/20 0.44
▸ EIF4H Q15056 1/20 0.44
▸ KDM4E B2RXH2 1/20 0.43
▸ ABL1 P00519 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27195689 0.88 CACNA1H (0.51) MAPTSMN1; SMN2KMT2APOLBCACNA1H
SCHEMBL27195723 0.84 CACNA1H (0.51) MAPTSMN1; SMN2KMT2APOLBCACNA1H
SCHEMBL27195697 0.82 SMN1; SMN2 (0.67) MAPTSMN1; SMN2KMT2APOLBCACNA1H
Hydrochloric Acid SCHEMBL30863412 0.81 KMT2A (0.48) MAPTSMN1; SMN2KMT2APOLBCACNA1H
SCHEMBL27195712 0.81 KMT2A (0.73) MAPTSMN1; SMN2KMT2APOLBCACNA1H
SCHEMBL27195737 0.78 KMT2A (0.56) MAPTSMN1; SMN2KMT2APOLBCACNA1H
SCHEMBL27195729 0.77 CACNA1H (0.52) MAPTSMN1; SMN2KMT2APOLBCACNA1H
SCHEMBL27195733 0.74 TRPV1 (0.59) MAPTSMN1; SMN2KMT2APOLBCACNA1H
SCHEMBL27195708 0.74 CACNA1H (0.51) SMN1; SMN2KMT2APOLBCACNA1HCACNA1B
SCHEMBL27195722 0.74 CACNA1H (0.53) MAPTSMN1; SMN2KMT2APOLBCACNA1H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4581017-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2025-07-09 — — EP claimed
WO-2024079072-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS BIODOL THERAPEUTICS (FR) 2024-04-18 — — WO claimed
EP-4353712-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2024-04-17 — — EP claimed
EP-4581017-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2025-07-09 — — EP disclosed
WO-2024079072-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS BIODOL THERAPEUTICS (FR) 2024-04-18 — — WO disclosed
EP-4353712-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2024-04-17 — — EP disclosed
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