SCHEMBL27195697

SCHEMBL27195697

CN(C)CCOc1ccc(C(=O)Nc2cccc3ncccc23)cc1

nearest known ligand 0.67

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 2/20 0.67
▸ KMT2A Q03164 6/20 0.62
▸ MEN1 O00255 5/20 0.62
▸ HDAC6 Q9UBN7 1/20 0.62
▸ PABPC1 P11940 2/20 0.61
▸ EIF4H Q15056 2/20 0.61
▸ L3MBTL1 Q9Y468 3/20 0.61
▸ RECQL P46063 1/20 0.55
▸ POLB P06746 3/20 0.55
▸ HSD17B10 Q99714 1/20 0.54
▸ CYP1A2 P05177 1/20 0.53
▸ CYP3A4 P08684 1/20 0.53
▸ CLK1 P49759 1/20 0.53
▸ CACNA1H O95180 3/20 0.53
▸ CACNA1B Q00975 2/20 0.53
▸ ALDH1A1 P00352 1/20 0.51
▸ MAPT P10636 1/20 0.51
▸ HDAC1 Q13547 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30863494 0.87 MEN1 (0.57) SMN1; SMN2KMT2AMEN1HDAC6PABPC1
SCHEMBL27195715 0.87 MEN1 (0.57) SMN1; SMN2KMT2AMEN1HDAC6PABPC1
SCHEMBL27195737 0.87 KMT2A (0.56) SMN1; SMN2KMT2AMEN1HDAC6PABPC1
SCHEMBL27195712 0.83 KMT2A (0.73) SMN1; SMN2KMT2AMEN1HDAC6L3MBTL1
SCHEMBL30863469 0.83 MAPT (0.58) SMN1; SMN2KMT2AMEN1PABPC1EIF4H
SCHEMBL27195689 0.82 CACNA1H (0.51) SMN1; SMN2KMT2AMEN1PABPC1EIF4H
SCHEMBL27195692 0.82 MAPT (0.49) SMN1; SMN2KMT2AMEN1PABPC1EIF4H
SCHEMBL27195700 0.81 MEN1 (0.54) SMN1; SMN2KMT2AMEN1PABPC1EIF4H
SCHEMBL30863532 0.81 MEN1 (0.54) SMN1; SMN2KMT2AMEN1PABPC1EIF4H
SCHEMBL27195708 0.81 CACNA1H (0.51) SMN1; SMN2KMT2AHDAC6POLBCACNA1H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4581017-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2025-07-09 — — EP claimed
WO-2024079072-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS BIODOL THERAPEUTICS (FR) 2024-04-18 — — WO claimed
EP-4353712-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2024-04-17 — — EP claimed
EP-4581017-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2025-07-09 — — EP disclosed
WO-2024079072-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS BIODOL THERAPEUTICS (FR) 2024-04-18 — — WO disclosed
EP-4353712-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2024-04-17 — — EP disclosed
Send feedback