SCHEMBL27195722

SCHEMBL27195722

CN(C)CCOc1ccc(C(=O)Nc2cccc3cnncc23)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CACNA1H O95180 3/20 0.53
▸ CACNA1B Q00975 2/20 0.53
▸ HDAC1 Q13547 2/20 0.49
▸ KMT2A Q03164 2/20 0.48
▸ POLB P06746 1/20 0.48
▸ NPC1 O15118 2/20 0.48
▸ RAB9A P51151 2/20 0.48
▸ HRH3 Q9Y5N1 1/20 0.47
▸ GRIN2D O15399 1/20 0.45
▸ GRIN2C Q14957 1/20 0.45
▸ CHRNB2 P17787 4/20 0.44
▸ CHRNA4 P43681 4/20 0.44
▸ CHRNB4 P30926 3/20 0.44
▸ CHRNA3 P32297 3/20 0.44
▸ SMN1; SMN2 Q16637 2/20 0.44
▸ MAPT P10636 2/20 0.44
▸ LMNA P02545 1/20 0.44
▸ TP53 P04637 1/20 0.44
▸ HSD17B10 Q99714 1/20 0.44
▸ KDM4E B2RXH2 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27195708 0.87 CACNA1H (0.51) CACNA1HCACNA1BHDAC1KMT2APOLB
SCHEMBL27195733 0.87 TRPV1 (0.59) CACNA1HCACNA1BHDAC1KMT2APOLB
SCHEMBL27195712 0.81 KMT2A (0.73) CACNA1HCACNA1BKMT2APOLBNPC1
SCHEMBL27195697 0.80 SMN1; SMN2 (0.67) CACNA1HCACNA1BHDAC1KMT2APOLB
SCHEMBL27195737 0.78 KMT2A (0.56) CACNA1HCACNA1BHDAC1KMT2APOLB
SCHEMBL30863430 0.74 KMT2A (0.49) CACNA1HCACNA1BHDAC1KMT2ANPC1
SCHEMBL27195800 0.74 CACNA1H (0.48) CACNA1HCACNA1BHDAC1NPC1RAB9A
SCHEMBL27195732 0.74 CACNA1H (0.48) CACNA1HCACNA1BHDAC1NPC1RAB9A
SCHEMBL30863471 0.74 CACNA1H (0.48) CACNA1HCACNA1BHDAC1NPC1RAB9A
SCHEMBL27195689 0.74 CACNA1H (0.51) CACNA1HCACNA1BHDAC1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4581017-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2025-07-09 — — EP claimed
WO-2024079072-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS BIODOL THERAPEUTICS (FR) 2024-04-18 — — WO claimed
EP-4353712-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2024-04-17 — — EP claimed
EP-4581017-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2025-07-09 — — EP disclosed
WO-2024079072-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS BIODOL THERAPEUTICS (FR) 2024-04-18 — — WO disclosed
EP-4353712-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2024-04-17 — — EP disclosed
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