Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | WDR5 | P61964 | 6/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | JAK1 | P23458 | 1/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GALK1 | P51570 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30863450 | 1.00 | TRPV1 (0.57) | TRPV1CNR1WDR5BRD4JAK1 | |
| SCHEMBL27195706 | 0.84 | TRPV1 (0.58) | TRPV1CNR1MAPK1 | |
| SCHEMBL27195727 | 0.84 | CNR1 (0.53) | TRPV1CNR1NPY5RMAPK1MAPT | |
| SCHEMBL30863422 | 0.79 | WDR5 (0.49) | WDR5FGFR1FGFR2MAPT | |
| SCHEMBL27195721 | 0.78 | SIRT6 (0.55) | TRPV1CNR1NPY5RMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL30863459 | 0.76 | CNR1 (0.57) | TRPV1CNR1NPY5RMAPK1MAPT | |
| SCHEMBL27195713 | 0.76 | HDAC6 (0.60) | TRPV1CNR1MAPK1MAPTKDM4E | |
| SCHEMBL27195758 | 0.76 | AURKA (0.53) | — | |
| SCHEMBL30863515 | 0.75 | TRPV1 (0.59) | TRPV1NPY5RMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL30863517 | 0.75 | CNR1 (0.51) | TRPV1CNR1MAPTKDM4EGALK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4353712-A1 | NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS | Biodol Therapeutics (FR) | 2024-04-17 | — | — | EP | claimed |
| EP-4353712-A1 | NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS | Biodol Therapeutics (FR) | 2024-04-17 | — | — | EP | disclosed |