Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.60 |
| ▸ | FAAH | O00519 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.45 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.43 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27199086 | 1.00 | SLC6A5 (0.60) | SLC6A5FAAHCNR1CNR2HRH3 | |
| SCHEMBL27199097 | 0.89 | SLC6A5 (0.68) | SLC6A5FAAHCNR1CNR2HRH3 | |
| SCHEMBL27199088 | 0.89 | SLC6A5 (0.68) | SLC6A5FAAHCNR1CNR2HRH3 | |
| SCHEMBL28808810 | 0.88 | SLC6A5 (0.69) | SLC6A5FAAHCNR1CNR2HRH3 | |
| SCHEMBL21724574 | 0.85 | SLC6A5 (0.63) | SLC6A5FAAHCNR1CNR2HRH3 | |
| SCHEMBL19051541 | 0.85 | SLC6A5 (0.50) | SLC6A5FAAHCNR1CNR2HRH3 | |
| SCHEMBL28518101 | 0.84 | CTSB (0.60) | SLC6A5RENCTSBCTSK | |
| SCHEMBL28520371 | 0.84 | SLC6A5 (0.62) | SLC6A5FAAHCNR1CNR2SLC15A2 | |
| SCHEMBL27199089 | 0.83 | SLC6A5 (0.66) | SLC6A5FAAHCNR1CNR2SLC15A2 | |
| SCHEMBL19051544 | 0.83 | SLC6A5 (0.50) | SLC6A5FAAHCNR1CNR2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240124520-A1 | N-ACYLATED HISTIDINE DIPEPTIDES AS ANTICANCER AGENTS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2024-04-18 | — | — | US | claimed |
| CN-114585635-A | N-acylated histidine dipeptides as anti-cancer agents | 小利兰·斯坦福大学托管委员会 | 2022-06-03 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240124520-A1 | N-ACYLATED HISTIDINE DIPEPTIDES AS ANTICANCER AGENTS | NAALAD2, ASNS, AMDHD2 | SLC6A5 2993/4885FAAH 1636/4885CNR1 4857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.