Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 4/20 | 0.40 |
| ▸ | FLT1 | P17948 | 2/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27199806 | 0.88 | LATS1 (0.47) | CSNK2A2CSNK2A1CSNK2BNPY5RADORA3 | |
| SCHEMBL27199802 | 0.86 | CSNK2A1 (0.52) | CSNK2A2CSNK2A1CSNK2BERBB2DYRK1A | |
| SCHEMBL27199804 | 0.85 | LATS1 (0.50) | NPY5RDYRK1AADORA3KDM4EPKM | |
| SCHEMBL27199813 | 0.85 | KDM1A (0.45) | KDM4ENPC1PKMHPGDRAB9A | |
| SCHEMBL27199809 | 0.79 | TGFBR1 (0.40) | CSNK2A1KDRDYRK1AKDM4ENPC1 | |
| SCHEMBL27199801 | 0.79 | LATS1 (0.51) | CSNK2A1KDRFLT1SMN1; SMN2EGFR | |
| SCHEMBL31485514 | 0.78 | CSNK2A2 (0.44) | CSNK2A2CSNK2A1CSNK2BERBB2KDR | |
| SCHEMBL27074288 | 0.78 | CSNK2A1 (0.68) | CSNK2A2CSNK2A1CSNK2BDYRK1APIM1 | |
| SCHEMBL30866442 | 0.77 | CHEK1 (0.43) | DYRK1AKDM4ENPC1ALDH1A1PKM | |
| SCHEMBL27199812 | 0.77 | CSNK2A1 (0.53) | CSNK2A2CSNK2A1CSNK2BERBB2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11964976-B1 | Substituted pyrido[3′,4′:4,5]pyrrolo[3,2-c][1,6]naphthyridines as CK2 inhibitors | King Faisal University (SA) | 2024-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11964976-B1 | Substituted pyrido[3′,4′:4,5]pyrrolo[3,2-c][1,6]naphthyridines as CK2 inhibitors | CKS2, CDK2, CDK1 | CSNK2A2 13/4885CSNK2A1 9/4885CSNK2B 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.