Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LATS1 | O95835 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.45 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TLR3 | O15455 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27199806 | 0.87 | LATS1 (0.47) | LATS1ACHEABCG2MEN1KMT2A | |
| SCHEMBL27199812 | 0.87 | CSNK2A1 (0.53) | ACHEABCG2MEN1KMT2APTK6 | |
| SCHEMBL27199810 | 0.85 | CSNK2A2 (0.47) | ABCG2NPY5RKDM4EPKMRAB9A | |
| SCHEMBL27199813 | 0.84 | KDM1A (0.45) | MEN1KMT2AMAPTKDM4EPKM | |
| SCHEMBL27171380 | 0.80 | KMT2A (0.45) | LATS1ACHEABCG2MEN1KMT2A | |
| SCHEMBL31485594 | 0.80 | LATS1 (0.56) | LATS1ABCG2MEN1KMT2AABCC1 | |
| SCHEMBL27074286 | 0.79 | CSNK2A1 (0.57) | CLK1CLK2CLK3CDK5DYRK1A | |
| SCHEMBL27199809 | 0.79 | TGFBR1 (0.40) | LATS1ACHEMEN1KMT2AMAPT | |
| SCHEMBL27199801 | 0.79 | LATS1 (0.51) | LATS1ACHEABCG2MAPTKIT | |
| SCHEMBL27092621 | 0.78 | LATS1 (0.51) | LATS1ACHEABCG2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11964976-B1 | Substituted pyrido[3′,4′:4,5]pyrrolo[3,2-c][1,6]naphthyridines as CK2 inhibitors | King Faisal University (SA) | 2024-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11964976-B1 | Substituted pyrido[3′,4′:4,5]pyrrolo[3,2-c][1,6]naphthyridines as CK2 inhibitors | CKS2, CDK2, CDK1 | LATS1 974/4885ACHE 606/4885ABCG2 2679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.