Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | TENT4A | Q5XG87 | 1/20 | 0.36 |
| ▸ | TENT4B | Q8NDF8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | KIF5B | P33176 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27200110 | 0.78 | CYP2B6 (0.39) | CYP2B6TENT4ATENT4BKDM4EUSP2 | |
| SCHEMBL31365216 | 0.78 | CYP2B6 (0.39) | CYP2B6TENT4ATENT4BKDM4EUSP2 | |
| SCHEMBL31365215 | 0.78 | CYP2B6 (0.39) | CYP2B6TENT4ATENT4BKDM4EUSP2 | |
| SCHEMBL26967891 | 0.74 | PDPK1 (0.36) | L3MBTL1 | |
| SCHEMBL27200131 | 0.73 | CCR5 (0.42) | NPC1RAB9ASMPD1 | |
| SCHEMBL21465027 | 0.73 | HTR2A (0.35) | CYP2B6TENT4ATENT4BCYP1A2LMNA | |
| SCHEMBL22952875 | 0.73 | HTR2A (0.35) | CYP2B6TENT4ATENT4BCYP1A2LMNA | |
| SCHEMBL21331710 | 0.73 | MAPT (0.43) | KDM4EUSP2RETKIF5BL3MBTL1 | |
| SCHEMBL611267 | 0.73 | PIK3CA (0.36) | CYP2B6TENT4ATENT4BKDM4EUSP2 | |
| SCHEMBL27200114 | 0.73 | RET (0.34) | CYP2B6TENT4ATENT4BKDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025008288-A1 | 9-OXO-9,10-DIHYDRO-6H-PYRANO[3,2-B:4,5-B']DIPYRIDINE-8-CARBOXYLIC ACID DERIVATIVES | CENTENARA LABS AG (CH) | 2025-01-09 | — | — | WO | disclosed |
| US-11964986-B1 | 9-oxo-9,10-dihydro-6H-pyrano[3,2-b:4,5-b′]dipyridine-8-carboxylic acid derivatives | REJUVERON TELOMERE THERAPEUTICS AG (CH) | 2024-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11964986-B1 | 9-oxo-9,10-dihydro-6H-pyrano[3,2-b:4,5-b′]dipyridine-8-carboxylic acid derivatives | DPP9, DPYD, QDPR | CYP2B6 26/4885TENT4A 2925/4885TENT4B 2915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.