Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 11/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Abeprazan SCHEMBL18196939 | 0.91 | HTR6 (0.39) | HTR6HTR2AHTR2CMEN1MAPT | |
| Abeprazan SCHEMBL29719476 | 0.91 | HTR6 (0.39) | HTR6HTR2AHTR2CMEN1MAPT | |
| Abeprazan SCHEMBL29443418 | 0.91 | HTR6 (0.39) | HTR6HTR2AHTR2CMEN1MAPT | |
| Abeprazan SCHEMBL19385615 | 0.90 | HTR6 (0.40) | HTR6HTR2AHTR2CMEN1MAPT | |
| SCHEMBL25314470 | 0.89 | SLC6A4 (0.37) | HTR6PTGS1PTGS2POLBKMT2A | |
| SCHEMBL30250179 | 0.89 | SLC6A4 (0.37) | HTR6PTGS1PTGS2POLBKMT2A | |
| SCHEMBL26650833 | 0.89 | MEN1 (0.37) | KCNH2PTGS1PTGS2MEN1MAPT | |
| SCHEMBL30250130 | 0.89 | MEN1 (0.37) | KCNH2PTGS1PTGS2MEN1MAPT | |
| Abeprazan SCHEMBL29201776 | 0.88 | HTR6 (0.38) | HTR6CYP3A4CYP2D6HTR2AHTR2C | |
| SCHEMBL18190937 | 0.88 | HTR6 (0.35) | HTR6HTR2AHTR2CMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4356900-A1 | NOVEL INJECTABLE FORMULATION COMPRISING 1-(5-(2,4-DIFLUOROPHENYL)-1-((3-FLUOROPHENYL)SULFONYL)-4-METHOXY-1H-PYRROL-3-YL)-N-METHYLMETHANAMINE | Daewoong Pharmaceutical Co., Ltd. (KR) | 2024-04-24 | — | — | EP | disclosed |