Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 16/20 | 0.50 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23620977 | 0.84 | GPR119 (0.52) | GPR119SCN9AKDM4EPKM | |
| SCHEMBL23620967 | 0.84 | CA2 (0.55) | GPR119SCN9A | |
| SCHEMBL20502393 | 0.84 | CA2 (0.49) | GPR119STS | |
| SCHEMBL23620931 | 0.80 | GPR119 (0.48) | GPR119SCN9AKDM4EPKM | |
| SCHEMBL23620932 | 0.79 | GPR119 (0.47) | GPR119STS | |
| SCHEMBL30307812 | 0.79 | GPR119 (0.47) | GPR119STS | |
| SCHEMBL27200508 | 0.78 | CA2 (0.47) | GPR119STSKDM4EPKM | |
| SCHEMBL5763005 | 0.77 | GPR119 (0.51) | GPR119SCN9AKDM4EPKM | |
| SCHEMBL6011532 | 0.75 | GPR119 (0.50) | GPR119KDM4EPKM | |
| SCHEMBL30307816 | 0.75 | GPR119 (0.53) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3596059-B1 | HETEROCYCLIC COMPOUNDS USEFUL AS DUAL ATX/CA INHIBITORS | HOFFMANN LA ROCHE (CH) | 2024-04-24 | — | — | EP | disclosed |