Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | GCK | P35557 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27200517 | 0.85 | GPR119 (0.46) | GPR119 | |
| SCHEMBL23620944 | 0.80 | CA2 (0.46) | CA2GPR119CA12CA1CA9 | |
| SCHEMBL23620981 | 0.79 | CA2 (0.49) | CA2GPR119 | |
| SCHEMBL23620983 | 0.78 | SCN9A (0.42) | CA2GPR119CA12CA1CA9 | |
| SCHEMBL23620948 | 0.76 | GPR119 (0.47) | GPR119 | |
| SCHEMBL2666840 | 0.75 | GPR119 (0.46) | GPR119HPGD | |
| SCHEMBL1181631 | 0.75 | GPR119 (0.54) | GPR119HPGD | |
| SCHEMBL23620980 | 0.74 | GPR119 (0.55) | CA2GPR119CHRNA7 | |
| SCHEMBL17397821 | 0.72 | GPR119 (0.43) | GPR119HPGD | |
| SCHEMBL23620987 | 0.72 | GPR119 (0.49) | CA2GPR119MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3596059-B1 | HETEROCYCLIC COMPOUNDS USEFUL AS DUAL ATX/CA INHIBITORS | HOFFMANN LA ROCHE (CH) | 2024-04-24 | — | — | EP | disclosed |