Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 10/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 9/20 | 0.35 |
| ▸ | ITGB7 | P26010 | 7/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28828644 | 0.90 | EPHX1 (0.35) | ITGA4ITGB1ITGB7MMP2MMP9 | |
| SCHEMBL29121324 | 0.88 | FFAR4 (0.35) | EPHX1 | |
| SCHEMBL29228177 | 0.88 | MTNR1B (0.36) | KDM4ESTSABCB1ABCC1 | |
| SCHEMBL29228166 | 0.88 | FFAR4 (0.35) | EPHX1 | |
| SCHEMBL29228407 | 0.86 | ABCB1 (0.36) | STSABCB1 | |
| SCHEMBL29121331 | 0.84 | EPHX1 (0.35) | MMP2MMP9EPHX1STS | |
| SCHEMBL29228203 | 0.82 | AR (0.41) | STS | |
| SCHEMBL23363108 | 0.81 | ITGA4 (0.38) | ITGA4ITGB1ITGB7MMP2MMP9 | |
| SCHEMBL29121217 | 0.81 | CYP2C19 (0.36) | ITGA4ITGB1EPHX1KDM4E | |
| SCHEMBL27200901 | 0.81 | ITGA4 (0.38) | ITGA4ITGB1ITGB7MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114746422-B | Derivatives having 1,2,3, 4-tetrahydronaphthalene moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-03-12 | — | — | CN | claimed |
| CN-114746422-A | Novel derivatives having 1,2,3, 4-tetrahydronaphthalene moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2022-07-12 | — | — | CN | claimed |
| EP-4041734-B1 | DERIVATIVES HAVING 1,2,3,4-TETRAHYDRONAPHTHALENE MOIETY OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | YUHAN CORP (KR) | 2024-04-24 | — | — | EP | disclosed |
| CN-114746422-B | Derivatives having 1,2,3, 4-tetrahydronaphthalene moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2024-03-12 | — | — | CN | disclosed |
| CN-114746422-A | Novel derivatives having 1,2,3, 4-tetrahydronaphthalene moiety or pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the same | 柳韩洋行 | 2022-07-12 | — | — | CN | disclosed |