Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.35 |
| ▸ | ACLY | P53396 | 4/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | MTHFD1 | P11586 | 1/20 | 0.33 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2183071 | 0.88 | GPR119 (0.44) | GPR119 | |
| SCHEMBL2184142 | 0.83 | SLC6A9 (0.49) | GPR119SLC6A9 | |
| SCHEMBL2733039 | 0.82 | MEN1 (0.32) | FFAR4 | |
| SCHEMBL2721042 | 0.81 | GPR119 (0.33) | GPR119FFAR4 | |
| SCHEMBL12414611 | 0.81 | GPR119 (0.42) | GPR119 | |
| SCHEMBL2731984 | 0.81 | FFAR4 (0.34) | SLC6A9FFAR4 | |
| SCHEMBL2720999 | 0.80 | FFAR4 (0.34) | FFAR4 | |
| SCHEMBL2720992 | 0.79 | FFAR4 (0.35) | FFAR4 | |
| SCHEMBL2182681 | 0.75 | GPR119 (0.40) | GPR119 | |
| SCHEMBL12413810 | 0.75 | MAPT (0.36) | GPR119FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445878-A1 | NEW COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS RELATING THERETO | Boehringer Ingelheim International GmbH (DE) | 2012-05-02 | — | — | EP | disclosed |
| WO-2010149684-A1 | NEW COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS RELATING THERETO | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-12-29 | — | — | WO | disclosed |