Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | ERN1 | O75460 | 2/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPRA | P18433 | 1/20 | 0.35 |
| ▸ | PTPRB | P23467 | 1/20 | 0.35 |
| ▸ | PTPRE | P23469 | 1/20 | 0.35 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | BCR | P11274 | 1/20 | 0.31 |
| ▸ | RAF1 | P04049 | 3/20 | 0.31 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL203554 | 0.78 | PTPN1 (0.50) | PTPRCPTPN2PTPN1PTPRAPTPRB | |
| SCHEMBL1670382 | 0.76 | PTPN2 (0.37) | ARERN1PTPRCPTPN2PTPN1 | |
| SCHEMBL8282570 | 0.76 | ERN1 (0.42) | ERN1PTPRCPTPN2PTPN1PTPRA | |
| SCHEMBL26930859 | 0.76 | PTPRC (0.37) | ARPTPRCPTPN2PTPN1PTPRA | |
| SCHEMBL3736638 | 0.73 | PTPRC (0.35) | ARPTPRCPTPN2PTPN1PTPRA | |
| SCHEMBL27201535 | 0.73 | HPGD (0.50) | ALDH1A1MAPTMEN1CYP1A2POLB | |
| SCHEMBL204305 | 0.72 | SOS1 (0.45) | ALDH1A1MAPTABL1MEN1LMNA | |
| SCHEMBL20308954 | 0.72 | TRPV1 (0.39) | PTPRCPTPN2PTPN1PTPRAPTPRB | |
| SCHEMBL27201517 | 0.71 | ALDH1A1 (0.51) | MAPK1TDP1ALDH1A1MAPTMEN1 | |
| Thiophene SCHEMBL28659857 | 0.70 | PTPN2 (0.40) | ARPTPN2PTPN1PTPN6TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240132464-A1 | HETEROCYCLIC COMPOUNDS AS E3 LIGASE INHIBITORS | ACCUTAR BIOTECHNOLOGY INC. (US) | 2024-04-25 | — | — | US | disclosed |
| WO-2024073502-A1 | HETEROCYCLIC COMPOUNDS AS E3 LIGASE INHIBITORS | ACCUTAR BIOTECHNOLOGY INC. (US) | 2024-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132464-A1 | HETEROCYCLIC COMPOUNDS AS E3 LIGASE INHIBITORS | GID4, MDM2, XIAP | AR 2142/4885ERN1 1734/4885PTPRC 740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.