SCHEMBL2720170

SCHEMBL2720170

C/C(=C\C1CCCO1)C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
GABRA1 P14867 1/20 0.33
TSHR P16473 1/20 0.33
GABRG2 P18507 1/20 0.33
RXRA P19793 1/20 0.33
GABRB3 P28472 1/20 0.33
RXRB P28702 1/20 0.33
GABRB2 P47870 1/20 0.33
RXRG P48443 1/20 0.33
KMT2A Q03164 2/20 0.33
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
HTT P42858 1/20 0.31
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL261261 1.00 ALDH1A1 (0.33) ALDH1A1GABRA1TSHRGABRG2RXRA
SCHEMBL18269630 0.94 ALDH1A1 (0.33) ALDH1A1GABRA1TSHRGABRG2RXRA
SCHEMBL216309 0.94 ALDH1A1 (0.33) ALDH1A1GABRA1TSHRGABRG2RXRA
SCHEMBL216308 0.94 ALDH1A1 (0.33) ALDH1A1GABRA1TSHRGABRG2RXRA
SCHEMBL1394143 0.90 ALDH1A1 (0.36) ALDH1A1GABRA1TSHRGABRG2RXRA
SCHEMBL4309465 0.90 ALDH1A1 (0.36) ALDH1A1GABRA1TSHRGABRG2RXRA
SCHEMBL23923025 0.86 CD81 (0.33) ALDH1A1
SCHEMBL8192002 0.83 HPGD (0.35) ALDH1A1KMT2ALMNAPOLBHPGD
SCHEMBL19510386 0.81
SCHEMBL29122247 0.80 HPGD (0.33) ALDH1A1KMT2AHPGDHTTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3956334-B1 COMPOUNDS FOR OPTICALLY ACTIVE DEVICES AMO Ireland (IE) 2025-09-24 EP claimed
EP-4182737-B1 OPTICALLY ACTIVE DEVICES AMO Ireland (IE) 2024-07-03 EP claimed
EP-3889135-B1 COMPOUNDS FOR OPTICALLY ACTIVE DEVICES AMO Ireland (IE) 2023-08-02 EP claimed
US-20220296417-A1 NON-DEGRADING SWELLABLE POLYMERS AS MATERIALS FOR BIOMEDICAL DEVICES INNFOCUS, INC. 2022-09-22 US claimed
EP-3164097-B1 MILL BLANKS BASED ON A POLYMERIZED, FRACTURE-TOUGH PROSTHESIS MATERIAL KULZER & CO GMBH (DE) 2022-05-11 EP claimed
EP-3975951-A1 NON-DEGRADING SWELLABLE POLYMERS AS MATERIALS FOR BIOMEDICAL DEVICES Innfocus, Inc. (US) 2022-04-06 EP claimed
EP-3894371-A1 METHOD FOR PRODUCING THIN TRANSPARENT CERAMIC PARTS, AND THIN TRANSPARENT CERAMIC PARTS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2021-10-20 EP claimed
EP-3583092-B1 COMPOUNDS FOR OPTICALLY ACTIVE DEVICES MERCK PATENT GMBH (DE) 2021-05-26 EP claimed
US-11007302-B2 Auto-polymerizable prosthetic material and polymerized, fracture-tough prosthetic material with increased colour stability KULZER GMBH (DE) 2021-05-18 US claimed
WO-2020247365-A1 NON-DEGRADING SWELLABLE POLYMERS AS MATERIALS FOR BIOMEDICAL DEVICES INNFOCUS, INC. (US) 2020-12-10 WO claimed
WO-2016001242-A1 MILL BLANKS BASED ON A POLYMERIZED, FRACTURE-TOUGH PROSTHESIS MATERIAL HERAEUS KULZER GMBH (DE) 2016-01-07 WO claimed
WO-2016001236-A1 AUTO-POLYMERIZABLE PROSTHETIC MATERIAL AND POLYMERIZED, FRACTURE-TOUGH PROSTHETIC MATERIAL WITH INCREASED COLOUR STABILITY HERAEUS KULZER GMBH (DE) 2016-01-07 WO claimed
US-20150099817-A1 MOULDED PARTS MADE OF PMMA POWDER AS SIMPLE DOSING AID IN THE MANUFACTURE OF DENTAL PROSTHESES HERAEUS KULZER GMBH (DE) 2015-04-09 US claimed
EP-2813541-A1 Moulded parts made of PMMA powder as simple dosing aid in the manufacture of dental prostheses Heraeus Kulzer GmbH (DE) 2014-12-17 EP claimed
EP-2491065-B1 HYDROPHILICALLY-MODIFIED SILICONE COMPOSITIONS DOW CORNING (US) 2014-11-26 EP claimed
EP-2502942-A1 Use of dual-hardening compounds in metallography Heraeus Kulzer GmbH & Co. KG (DE) 2012-09-26 EP claimed
EP-2336214-B1 A two-component adhesive suitable for construction purposes, its use and the cured structural bonds obtained thereby HILTI AG (LI) 2012-05-02 EP claimed
US-5229244-A Dry processible photosensitive composition including photo-acid generator and optically clear polymer (co-polymer) blend that becomes tacky upon exposure to actinic radiation E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-07-20 US claimed
EP-0032249-B1 PROVISIONAL CROWN - AND - BRIDGE RESIN DEN-MAT, INC. (US) 1984-03-21 EP claimed
US-4352892-A POLYOLEFINS FIRMA CARL FREUDENBERG (DE) 1982-10-05 US claimed