Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.73 |
| ▸ | RAB9A | P51151 | 7/20 | 0.69 |
| ▸ | NPC1 | O15118 | 6/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | AHR | P35869 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29793247 | 1.00 | KMT2A (0.73) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2822763 | 0.83 | KMT2A (0.56) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29793209 | 0.83 | AHR (0.60) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3092361 | 0.82 | SMN1; SMN2 (1.00) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL31025870 | 0.81 | AHR (0.69) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2822758 | 0.79 | KMT2A (0.63) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL31637542 | 0.77 | KMT2A (0.51) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL19476627 | 0.75 | RAB9A (0.72) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8662298 | 0.75 | MEN1 (0.61) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1499710 | 0.74 | MAPT (0.70) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240132431-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132431-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | MGMT, MCL1, FANCF | KMT2A 721/4885MEN1 1437/4885RAB9A 2634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.