Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 6/20 | 0.58 |
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | XDH | P47989 | 1/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.50 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4593089 | 0.81 | POLB (0.56) | KMT2AKDM4ETP53NPC1RAB9A | |
| SCHEMBL4751754 | 0.80 | NPC1 (0.57) | MEN1KMT2ATP53MAPTNPC1 | |
| SCHEMBL4752431 | 0.80 | MEN1 (0.52) | MEN1KMT2AKDM4EGAAMAPT | |
| SCHEMBL19100236 | 0.80 | KDM4E (0.53) | MEN1KMT2AKDM4EGAA | |
| SCHEMBL6816234 | 0.78 | NAMPT (0.50) | KMT2AMAPTNPC1RAB9A | |
| SCHEMBL23246003 | 0.77 | GAA (0.63) | MEN1KMT2AKDM4EGAATP53 | |
| SCHEMBL27697586 | 0.76 | NPSR1 (0.54) | MEN1KMT2AGAATP53MAPT | |
| SCHEMBL30808836 | 0.75 | KMT2A (0.67) | MEN1KMT2AKDM4EGAATP53 | |
| SCHEMBL27202069 | 0.75 | KMT2A (0.73) | MEN1KMT2AKDM4EGAATP53 | |
| SCHEMBL29793247 | 0.75 | KMT2A (0.73) | MEN1KMT2AKDM4EGAATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840740-A1 | NEW INHIBITORS OF PLATELET AGGREGATION | Astra Pharmaceuticals Limited (GB) | 1998-05-13 | — | — | EP | claimed |
| WO-1997003084-A1 | NEW INHIBITORS OF PLATELET AGGREGATION | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-01-30 | — | — | WO | claimed |