Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 19/20 | 0.59 |
| ▸ | BCL2 | P10415 | 15/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 13/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30963857 | 0.84 | BCL2L1 (0.54) | BCL2L1BCL2MCL1BAK1 | |
| SCHEMBL27202053 | 0.83 | BCL2 (0.42) | BCL2L1BCL2MCL1MEN1KMT2A | |
| SCHEMBL1113832 | 0.81 | BCL2L1 (0.64) | BCL2L1BCL2MCL1 | |
| SCHEMBL29793288 | 0.80 | RAB9A (0.42) | BCL2L1BCL2MCL1MEN1KMT2A | |
| SCHEMBL1957094 | 0.79 | KDM4E (0.55) | MEN1KMT2A | |
| SCHEMBL10222702 | 0.77 | BCL2L1 (0.93) | BCL2L1BCL2MCL1BAK1 | |
| SCHEMBL29793079 | 0.77 | BCL2L1 (0.93) | BCL2L1BCL2MCL1BAK1 | |
| SCHEMBL2408475 | 0.77 | MAPT (0.52) | MEN1KMT2A | |
| SCHEMBL1960127 | 0.77 | KDM4E (0.67) | MEN1KMT2A | |
| SCHEMBL1957524 | 0.76 | MAPT (0.47) | BCL2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240132431-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-04-25 | — | — | US | disclosed |
| CN-107033043-B | N- replaces benzenesulfonyl-substituted benzene formyl amine compound and its prepares the purposes of drug | 中国人民解放军第二军医大学 | 2019-04-30 | — | — | CN | disclosed |
| CN-107033043-A | N- replaces benzenesulfonyl-substituted benzene formyl amine compound and its prepares the purposes of medicine | 中国人民解放军第二军医大学 | 2017-08-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132431-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | MGMT, MCL1, FANCF | BCL2L1 650/4885BCL2 131/4885MCL1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.