Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 11/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 11/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 10/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27202035 | 0.84 | BCL2L1 (0.40) | BCL2BCL2L1MCL1ALDH1A1MEN1 | |
| SCHEMBL27202085 | 0.83 | BCL2L1 (0.59) | BCL2BCL2L1MCL1MEN1KMT2A | |
| SCHEMBL26657506 | 0.81 | ALDH1A1 (0.46) | BCL2BCL2L1MCL1ALDH1A1MEN1 | |
| SCHEMBL29793288 | 0.80 | RAB9A (0.42) | BCL2BCL2L1MCL1ALDH1A1MEN1 | |
| SCHEMBL29793332 | 0.77 | BCL2L1 (0.65) | BCL2BCL2L1MCL1 | |
| SCHEMBL27202074 | 0.76 | BCL2L1 (0.40) | BCL2BCL2L1MCL1ALDH1A1MEN1 | |
| SCHEMBL30963880 | 0.76 | BCL2L1 (0.40) | BCL2BCL2L1MCL1ALDH1A1MEN1 | |
| SCHEMBL29080227 | 0.75 | ALDH1A1 (0.43) | BCL2BCL2L1MCL1ALDH1A1MEN1 | |
| SCHEMBL27202093 | 0.72 | NPC1 (0.41) | BCL2BCL2L1MCL1ALDH1A1MEN1 | |
| SCHEMBL30963920 | 0.71 | BCL2L1 (0.39) | BCL2BCL2L1MCL1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240132431-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132431-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | MGMT, MCL1, FANCF | BCL2 131/4885BCL2L1 650/4885MCL1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.