Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.49 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.49 |
| ▸ | GPR3 | P46089 | 1/20 | 0.47 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.43 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
| ▸ | GABRE | P78334 | 1/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27885016 | 0.83 | HASPIN (0.40) | ALKBH5FTOGPR3HASPINCXCR4 | |
| SCHEMBL27992450 | 0.80 | ALKBH5 (0.51) | ALKBH5FTOGPR3LIMK1GABRP | |
| SCHEMBL31402850 | 0.80 | UTS2R (0.44) | ALKBH5FTOGPR3CXCR4LIMK1 | |
| SCHEMBL15312161 | 0.79 | BCHE (0.44) | HASPINKDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL3333888 | 0.78 | DYRK1A (0.59) | ALKBH5FTOGPR3HASPINLIMK1 | |
| SCHEMBL16596110 | 0.77 | ALKBH5 (0.51) | ALKBH5FTOGPR3LIMK1GABRP | |
| SCHEMBL3339645 | 0.77 | ALKBH5 (0.51) | ALKBH5FTOGPR3LIMK1GABRP | |
| SCHEMBL3340225 | 0.77 | ALKBH5 (0.51) | ALKBH5FTOGPR3LIMK1GABRP | |
| SCHEMBL2214304 | 0.76 | MEN1 (0.44) | ALKBH5FTOGABRPGABRDGABRA1 | |
| SCHEMBL2729487 | 0.76 | BCHE (0.41) | HASPINBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2635575-A1 | CARBAZOLE AND CARBOLINE DERIVATIVES, AND PREPARATION AND THERAPEUTIC APPLICATIONS THEREOF | Philip Morris Products S.a.s. (CH) | 2013-09-11 | — | — | EP | disclosed |
| WO-2012059232-A1 | CARBAZOLE AND CARBOLINE DERIVATIVES, AND PREPARATION AND THERAPEUTIC APPLICATIONS THEREOF | PHILIP MORRIS PRODUCTS S.A (CH) | 2012-05-10 | — | — | WO | disclosed |