SCHEMBL272037

SCHEMBL272037

CSc1cccnc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30668848 1.00
Acetic Acid SCHEMBL28049616 0.88 ALDH1A1 (0.47)
Phosphonic Acid SCHEMBL9637901 0.88 MEN1 (0.41)
SCHEMBL9637905 0.82 MEN1 (0.38)
Propane SCHEMBL9823974 0.82 NOS3 (0.39)
SCHEMBL14749003 0.81
SCHEMBL23183097 0.80
SCHEMBL29896037 0.79 ALDH1A1 (0.50)
SCHEMBL2829221 0.79 ALDH1A1 (0.50)
SCHEMBL9548473 0.79 CYP2A6 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 374 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260000692-A1 Substituted N-(Pyridin-2-yl)Acetamide Derivatives as CDK12/13 Inhibitors AURIGENE ONCOLOGY LIMITED (IN) 2026-01-01 US claimed
CN-115286799-B Triblock polysiloxane quaternary ammonium salt and preparation method thereof 常熟市斯泰普新材料有限公司 2023-02-24 CN claimed
CN-115286799-A Triblock polysiloxane quaternary ammonium salt and preparation method thereof 常熟市斯泰普新材料有限公司 2022-11-04 CN claimed
EP-0230068-B1 USE OF A GEMINAL DIPHOSPHONIC ACID COMPOUND TO PREPARE A MEDICAMENT Norwich Eaton Pharmaceuticals, Inc. (US) 1992-07-15 EP claimed
US-20240252473-A1 Sulfoximines as inhibitors of NaV1.8 GRUENENTHAL GMBH (DE) 2024-08-01 US disclosed
WO-2024130673-A1 POLYMER AND PREPARATION METHOD THEREFOR 深圳华大生命科学研究院 2024-06-27 WO disclosed
CN-112638910-B New heterocyclic amine derivatives and pharmaceutical compositions containing the same 株式会社大熊制药 2024-06-11 CN disclosed
WO-2024103400-A1 POLYCYCLIC COMPOUND AS GPR75 ACTIVATOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF 水木未来(北京)科技有限公司 2024-05-23 WO disclosed
CN-117466884-A Heterocyclic compounds or salts thereof as ATR kinase inhibitors, pharmaceutical compositions containing same and uses thereof 德州大学系统董事会 2024-01-30 CN disclosed
EP-3846793-B1 EIF4E INHIBITORS AND USES THEREOF PIC THERAPEUTICS INC (US) 2024-01-24 EP disclosed
EP-3651768-B1 HETEROCYCLIC INHIBITORS OF ATR KINASE UNIV TEXAS (US) 2023-12-20 EP disclosed
WO-2023234759-A1 NOVEL SULFANONE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND USE THEREOF 한국과학기술연구원 2023-12-07 WO disclosed
EP-0232623-A1 1-Carbacephalosporin antibiotics ELI LILLY AND COMPANY (US) 1987-08-19 EP disclosed
US-4642341-A BACTERICIDES BRISTOL-MYERS COMPANY (US) 1987-02-10 US disclosed
EP-0209751-A2 Cephalosporin derivatives and bactericides containing the same MEIJI SEIKA KAISHA LTD. (JP) 1987-01-28 EP disclosed
US-4568682-A Certain N-lower-alkyl-2-(pyridin-3yl)-tetrahydrothiophene or tetrahydrothiopyran-2-carbothioamide-1-oxides having anti-hypertensive activity RHONE-POULENC SANTE (FR) 1986-02-04 US disclosed
US-4552696-A GRAMNEGATIVE AND GRAMPOSITIVE BATERIA BRISTOL-MYERS COMPANY (US) 1985-11-12 US disclosed
US-4474954-A Intermediates for cephalosporin derivatives BRISTOL-MYERS COMPANY (US) 1984-10-02 US disclosed
US-4394503-A BACTERICIDWS BRISTOL-MYERS COMPANY (US) 1983-07-19 US disclosed
US-4315005-A Cephalosporin antibiotics GLAXO GROUP LIMITED (GB) 1982-02-09 US disclosed