Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
| ▸ | KMO | O15229 | 5/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | HTR1F | P30939 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | APOL1 | O14791 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27165383 | 1.00 | HTR2A (0.43) | HTR2AHTR2CHDAC1HDAC2CHRM2 | |
| SCHEMBL30816404 | 0.84 | PDE8B (0.44) | HTR2AHTR2CCHRM2CHRM1CHRM3 | |
| SCHEMBL27204460 | 0.84 | HTR2A (0.46) | HTR2AHTR2CCHRM2CHRM1 | |
| SCHEMBL27165389 | 0.84 | HTR2A (0.46) | HTR2AHTR2CCHRM2CHRM1 | |
| SCHEMBL27165366 | 0.81 | HTR2A (0.49) | HTR2AHTR2CCHRM2CHRM1CHRM3 | |
| SCHEMBL27204372 | 0.81 | HTR2A (0.49) | HTR2AHTR2CCHRM2CHRM1CHRM3 | |
| SCHEMBL23119920 | 0.73 | CPT1A (0.43) | — | |
| SCHEMBL23119917 | 0.72 | TBXA2R (0.43) | — | |
| SCHEMBL27156794 | 0.71 | AURKA (0.35) | — | |
| SCHEMBL27156349 | 0.71 | AURKA (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044848-A1 | INDAZOLE DERIVATIVES AS SEROTONERGIC AGENTS USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | MINDSET PHARMA INC. (CA) | 2024-03-07 | — | — | WO | disclosed |