Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE8B | O95263 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30816422 | 0.87 | KDM4E (0.46) | PDE8BHTR2AHTR2CHTR2BIRAK4 | |
| SCHEMBL27165383 | 0.84 | HTR2A (0.43) | HTR2AHTR2CHTR1AHTR1BCHRM2 | |
| SCHEMBL27204380 | 0.84 | HTR2A (0.43) | HTR2AHTR2CHTR1AHTR1BCHRM2 | |
| SCHEMBL27165366 | 0.78 | HTR2A (0.49) | HTR2AHTR2CHTR1AHTR1BCHRM2 | |
| SCHEMBL27204372 | 0.78 | HTR2A (0.49) | HTR2AHTR2CHTR1AHTR1BCHRM2 | |
| SCHEMBL27156891 | 0.76 | PDE8B (0.48) | PDE8BALOX5APFEN1IRAK4IL1B | |
| SCHEMBL29819701 | 0.76 | PDE8B (0.48) | PDE8BALOX5APFEN1IRAK4IL1B | |
| SCHEMBL29819929 | 0.76 | PDE8B (0.48) | PDE8BALOX5APFEN1IRAK4IL1B | |
| SCHEMBL22450851 | 0.74 | IL1B (0.49) | HTR2AHTR2CAPPHTR1AADRA2A | |
| SCHEMBL27204460 | 0.73 | HTR2A (0.46) | HTR2AHTR2CHTR2BCHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4581018-A1 | INDAZOLE DERIVATIVES AS SEROTONERGIC AGENTS USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | Mindset Pharma Inc. (CA) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024044848-A1 | INDAZOLE DERIVATIVES AS SEROTONERGIC AGENTS USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | MINDSET PHARMA INC. (CA) | 2024-03-07 | — | — | WO | disclosed |