Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.69 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.52 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27171426 | 1.00 | LTA4H (0.70) | LTA4HKCNH2SCN5ASCN10ANOTUM | |
| SCHEMBL27204649 | 0.88 | LTA4H (0.58) | LTA4HKCNH2SCN5ASCN10ANOTUM | |
| SCHEMBL24665357 | 0.88 | LTA4H (0.58) | LTA4HKCNH2SCN5ASCN10ANOTUM | |
| SCHEMBL27204783 | 0.86 | LTA4H (0.68) | LTA4HKCNH2SCN5ASCN10ANOTUM | |
| SCHEMBL27171420 | 0.86 | LTA4H (0.68) | LTA4HKCNH2SCN5ASCN10ANOTUM | |
| SCHEMBL27171402 | 0.85 | LTA4H (0.67) | LTA4HKCNH2FFAR1SCN9AFPR2 | |
| SCHEMBL27204647 | 0.85 | LTA4H (0.67) | LTA4HKCNH2FFAR1SCN9AFPR2 | |
| SCHEMBL29123608 | 0.84 | LTA4H (0.52) | LTA4HKCNH2SCN5ASCN10ANOTUM | |
| SCHEMBL29123605 | 0.84 | LTA4H (0.52) | LTA4HKCNH2SCN5ASCN10ANOTUM | |
| SCHEMBL27204884 | 0.82 | LTA4H (0.50) | LTA4HKCNH2NOTUMMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117015537-A | Heteroaryl aminopropanol derivatives as inhibitors of LTA4H | 诺华股份有限公司 | 2023-11-07 | — | — | CN | claimed |
| US-11932630-B2 | Heteroaryl aminopropanol derivatives | NOVARTIS AG (CH) | 2024-03-19 | — | — | US | disclosed |
| CN-117015537-A | Heteroaryl aminopropanol derivatives as inhibitors of LTA4H | 诺华股份有限公司 | 2023-11-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11932630-B2 | Heteroaryl aminopropanol derivatives | CYP3A43, CYP11B2, ADRB3 | LTA4H 1006/4885KCNH2 1449/4885SCN5A 271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.