SCHEMBL2720679

SCHEMBL2720679

Cc1ccc2oc(OCC(=O)N(Cc3cccs3)c3ccccc3)cc(=O)c2c1

nearest known ligand 0.63

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 12/20 0.63
TP53 P04637 6/20 0.57
LMNA P02545 6/20 0.52
THRB P10828 1/20 0.47
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30582853 1.00 TRPM8 (0.63) TRPM8TP53LMNATHRBTDP1
SCHEMBL17230202 0.82 TP53 (0.55) TRPM8TP53LMNATHRB
SCHEMBL2717047 0.78 TRPM8 (1.00) TRPM8TP53
SCHEMBL30582815 0.77 TP53 (0.88) TRPM8TP53LMNATHRBTDP1
SCHEMBL2719111 0.77 TP53 (0.88) TRPM8TP53LMNATHRBTDP1
SCHEMBL2720196 0.75 KDM4E (0.50) TP53THRBTDP1
SCHEMBL2717945 0.74 TRPM8 (0.72) TRPM8TP53LMNA
SCHEMBL2717391 0.74 TRPM8 (0.84) TRPM8TP53LMNATHRBTDP1
SCHEMBL2721144 0.73 TRPM8 (0.71) TRPM8TP53LMNATHRBTDP1
SCHEMBL2716916 0.73 TRPM8 (0.78) TRPM8TP53LMNATHRBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025132323-A1 COMPOSITIONS COMPRISING A SUNSCREEN ACTIVE AGENT DSM-FIRMENICH AG (CH) 2025-06-26 WO disclosed
EP-3470407-B1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 FIRMENICH INCORPORATED (US) 2024-01-24 EP disclosed
CN-109414048-B Coated yeast formulation 弗门尼舍有限公司 2023-09-01 CN disclosed
EP-3478089-B1 PLATED YEAST FORMULATIONS FIRMENICH & CIE (CH) 2021-11-03 EP disclosed
US-11160894-B2 Perfume emanating device FIRMENICH SA (CH) 2021-11-02 US disclosed
US-11091734-B2 Plated yeast formulations FIRMENICH SA (CH) 2021-08-17 US disclosed
US-10953007-B2 Compounds useful as modulators of TRPM8 FIRMENICH INCORPORATED (US) 2021-03-23 US disclosed
US-10953007-B2 Compounds useful as modulators of TRPM8 FIRMENICH INCORPORATED (US) 2021-03-23 US disclosed
EP-3478089-A1 PLATED YEAST FORMULATIONS Firmenich SA (CH) 2019-05-08 EP disclosed
EP-3470407-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 Senomyx, Inc. (US) 2019-04-17 EP disclosed
US-20160317532-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 FIRMENICH INCORPORATED 2016-11-03 US disclosed
US-9394287-B2 Compounds useful as modulators of TRPM8 SENOMYX, INC. (US) 2016-07-19 US disclosed
US-9394287-B2 Compounds useful as modulators of TRPM8 SENOMYX, INC. (US) 2016-07-19 US disclosed
US-9394287-B2 Compounds useful as modulators of TRPM8 SENOMYX, INC. (US) 2016-07-19 US disclosed
US-20130324557-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 SENOMYX, INC. (US) 2013-12-05 US disclosed
EP-2635572-A2 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 Senomyx, Inc. (US) 2013-09-11 EP disclosed
WO-2012061698-A9 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 SENOMYX, INC. (US) 2012-09-13 WO disclosed
WO-2012061698-A9 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 SENOMYX, INC. (US) 2012-09-13 WO disclosed
WO-2012061698-A2 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 SENOMYX, INC. (US) 2012-05-10 WO disclosed
WO-2012061698-A2 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 SENOMYX, INC. (US) 2012-05-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11160894-B2 Perfume emanating device DPM1, SURF4, FAAH2 TRPM8 151/4885TP53 3063/4885LMNA 3524/4885
US-10953007-B2 Compounds useful as modulators of TRPM8 TRPM8, TRPM7, TRPM6 TRPM8 1/4885TP53 4485/4885LMNA 4155/4885
US-20160317532-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 TRPM8, TRPM7, TRPM6 TRPM8 1/4885TP53 4485/4885LMNA 4155/4885
US-20130324557-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 TRPM8, TRPM7, TRPM6 TRPM8 1/4885TP53 4485/4885LMNA 4155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.