⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19871923 | 0.70 | EPHX1 (0.39) | — | |
| SCHEMBL19748065 | 0.70 | — | — | |
| SCHEMBL22585266 | 0.70 | EPHX1 (0.30) | — | |
| SCHEMBL22585247 | 0.70 | EPHX1 (0.30) | — | |
| SCHEMBL15334701 | 0.69 | EPHX1 (0.42) | — | |
| SCHEMBL20934668 | 0.67 | ASGR1 (0.30) | — | |
| SCHEMBL27089050 | 0.67 | — | — | |
| SCHEMBL26967130 | 0.67 | — | — | |
| SCHEMBL25433101 | 0.65 | — | — | |
| SCHEMBL3810403 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240317706-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF | MONTE ROSA THERAPEUTICS AG (CH) | 2024-09-26 | — | — | US | disclosed |
| US-20240287064-A1 | TRICYCLIC COMPOUND USED AS GPR84 ANTAGONIST | Wuhan Humanwell Innovative Drug Research and Development Center Limited Company (CN) | 2024-08-29 | — | — | US | disclosed |
| EP-4361151-A1 | TRICYCLIC COMPOUND USED AS GPR84 ANTAGONIST | Wuhan Humanwell Innovative Drug Research and Development Center Limited Company (CN) | 2024-05-01 | — | — | EP | disclosed |