SCHEMBL27214569

SCHEMBL27214569

Cc1ccc(-c2cccc3c2OCC[C@H]3CN(C)C(=O)O)cn1

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 15/20 0.38
P2RX7 Q99572 1/20 0.35
SCN9A Q15858 1/20 0.35
HSD17B10 Q99714 1/20 0.35
KDM6B O15054 4/20 0.35
FFAR2 O15552 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27231120 1.00 KDM4C (0.38) KDM4CP2RX7SCN9AHSD17B10KDM6B
SCHEMBL27214624 0.91 KDM4C (0.36) KDM4CP2RX7KDM6B
SCHEMBL27231261 0.91 KDM4C (0.36) KDM4CP2RX7KDM6B
SCHEMBL29923158 0.87 SCN9A (0.34) KDM4CP2RX7SCN9AHSD17B10
SCHEMBL27214589 0.87 KDM4C (0.40) KDM4CKDM6B
SCHEMBL27214536 0.87 KDM4C (0.40) KDM4CKDM6B
SCHEMBL27215437 0.87 KDM4C (0.40) KDM4CKDM6B
SCHEMBL27214526 0.86 KDM4C (0.38) KDM4CP2RX7KDM6B
SCHEMBL27214581 0.86 KDM4C (0.38) KDM4CP2RX7KDM6B
SCHEMBL27214597 0.86 KDM4C (0.36) KDM4CKDM6B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240150330-A1 CHROMANS AND BENZOFURANS AS 5-HT1A AND TAAR1 AGONISTS SUNOVION PHARMACEUTICALS INC. (US) 2024-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240150330-A1 CHROMANS AND BENZOFURANS AS 5-HT1A AND TAAR1 AGONISTS TAAR1, HTR1A, HTR1F KDM4C 3293/4885P2RX7 99/4885SCN9A 1896/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.