Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.63 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NT5E | P21589 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19627845 | 1.00 | NR1I2 (0.63) | NR1I2S1PR3TP53MMP9MMP13 | |
| SCHEMBL6128184 | 1.00 | NR1I2 (0.63) | NR1I2S1PR3TP53MMP9MMP13 | |
| SCHEMBL4310857 | 1.00 | NR1I2 (0.63) | NR1I2S1PR3TP53MMP9MMP13 | |
| SCHEMBL14801970 | 0.98 | NR1I2 (0.61) | NR1I2S1PR3TP53MMP9MMP13 | |
| SCHEMBL19627843 | 0.98 | NR1I2 (0.61) | NR1I2S1PR3TP53MMP9MMP13 | |
| SCHEMBL15936841 | 0.97 | NR1I2 (0.60) | NR1I2S1PR3TP53MMP9MMP13 | |
| Ammonia Solution, Strong SCHEMBL28300034 | 0.97 | NR1I2 (0.60) | NR1I2S1PR3TP53MMP9MMP13 | |
| SCHEMBL16324578 | 0.97 | NR1I2 (0.60) | NR1I2S1PR3TP53MMP9MMP13 | |
| SCHEMBL16076634 | 0.97 | NR1I2 (0.59) | NR1I2S1PR3TP53MMP9MMP13 | |
| SCHEMBL1048442 | 0.94 | NR1I2 (0.73) | NR1I2S1PR3TP53MMP9MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240148753-A1 | METHOD AND COMPOSITION FOR REVERSING AND/OR INHIBITING ATHEROSCLEROSIS | Arjil Biotech Holding Company Limited (TW) | 2024-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240148753-A1 | METHOD AND COMPOSITION FOR REVERSING AND/OR INHIBITING ATHEROSCLEROSIS | PCSK9, APOB, PCSK7 | NR1I2 1247/4885S1PR3 1167/4885TP53 4605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.