Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MLNR | O43193 | 3/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | OXTR | P30559 | 2/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.33 |
| ▸ | NMT1 | P30419 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30846294 | 1.00 | SLC40A1 (0.39) | SLC40A1KMT2AL3MBTL1MLNRSCN9A | |
| SCHEMBL30846209 | 0.86 | MLNR (0.38) | SLC40A1MLNRSCN9AOXTRAVPR1A | |
| SCHEMBL27122387 | 0.86 | MLNR (0.38) | SLC40A1MLNRSCN9AOXTRAVPR1A | |
| SCHEMBL27144846 | 0.82 | KDM4E (0.43) | SLC40A1KMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL30846429 | 0.82 | KDM4E (0.43) | SLC40A1KMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL30846306 | 0.81 | SLC40A1 (0.42) | SLC40A1KMT2ALMNAHTTNAMPT | |
| SCHEMBL27118078 | 0.81 | SLC40A1 (0.42) | SLC40A1KMT2ALMNAHTTNAMPT | |
| SCHEMBL27122378 | 0.80 | MCL1 (0.37) | SLC40A1MLNR | |
| SCHEMBL30846261 | 0.79 | SLC40A1 (0.41) | SLC40A1SCN9ALMNAHTTSMN1; SMN2 | |
| SCHEMBL27121169 | 0.79 | SLC40A1 (0.41) | SLC40A1SCN9ALMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240150365-A1 | PYRIDINYLSULFONAMIDE COMPOUNDS AND THEIR USE IN THERAPY | HOTSPOT THERAPEUTICS, INC. | 2024-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240150365-A1 | PYRIDINYLSULFONAMIDE COMPOUNDS AND THEIR USE IN THERAPY | MALT1, BCL6, BCL6B | SLC40A1 816/4885KMT2A 974/4885L3MBTL1 3832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.