Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.41 |
| ▸ | OXTR | P30559 | 1/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NMT1 | P30419 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | CCR4 | P51679 | 1/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
| ▸ | TUBB | P07437 | 1/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27121169 | 1.00 | SLC40A1 (0.41) | SLC40A1OXTRAVPR1ALMNAHTT | |
| SCHEMBL30846429 | 0.88 | KDM4E (0.43) | SLC40A1OXTRAVPR1ALMNAHTT | |
| SCHEMBL27144846 | 0.88 | KDM4E (0.43) | SLC40A1OXTRAVPR1ALMNAHTT | |
| SCHEMBL27137458 | 0.80 | SLC40A1 (0.38) | SLC40A1OXTRAVPR1ALMNAHTT | |
| SCHEMBL30847864 | 0.80 | SLC40A1 (0.38) | SLC40A1OXTRAVPR1ALMNAHTT | |
| SCHEMBL27214916 | 0.79 | SLC40A1 (0.39) | SLC40A1OXTRAVPR1ALMNAHTT | |
| SCHEMBL30846294 | 0.79 | SLC40A1 (0.39) | SLC40A1OXTRAVPR1ALMNAHTT | |
| SCHEMBL27121198 | 0.79 | OXTR (0.38) | SLC40A1OXTRAVPR1ALMNAHTT | |
| SCHEMBL30846487 | 0.79 | OXTR (0.38) | SLC40A1OXTRAVPR1ALMNAHTT | |
| SCHEMBL27121152 | 0.79 | NMT1 (0.33) | SLC40A1OXTRAVPR1ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044344-A1 | PYRIDINYLSULFONAMIDE COMPOUNDS AND THEIR USE IN THERAPY | HOTSPOT THERAPEUTICS, INC. (US) | 2024-02-29 | — | — | WO | disclosed |