Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 11/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.38 |
| ▸ | ATXN2 | Q99700 | 3/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27215961 | 1.00 | MGLL (0.46) | MGLLENPP2ATXN2KCNH2CACNA1C | |
| SCHEMBL25261715 | 0.97 | MGLL (0.46) | MGLLENPP2ATXN2KCNH2CACNA1C | |
| SCHEMBL25254968 | 0.97 | MGLL (0.46) | MGLLENPP2ATXN2KCNH2CACNA1C | |
| SCHEMBL27215979 | 0.84 | MGLL (0.42) | MGLLENPP2ATXN2CYP11B1CYP11B2 | |
| SCHEMBL25254799 | 0.83 | MGLL (0.46) | MGLLKCNH2CACNA1CSCN5ACYP11B1 | |
| SCHEMBL25297074 | 0.83 | MGLL (0.46) | MGLLKCNH2CACNA1CSCN5ACYP11B1 | |
| SCHEMBL25290096 | 0.83 | MGLL (0.46) | MGLLKCNH2CACNA1CSCN5ACYP11B1 | |
| SCHEMBL25256421 | 0.82 | MGLL (0.44) | MGLLENPP2ATXN2CYP11B1CYP11B2 | |
| SCHEMBL25295070 | 0.82 | MGLL (0.44) | MGLLENPP2ATXN2CYP11B1CYP11B2 | |
| SCHEMBL25292183 | 0.82 | MGLL (0.44) | MGLLENPP2ATXN2CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11981661-B2 | Heterocyclic compounds | HOFFMANN-LA ROCHE INC. (US) | 2024-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11981661-B2 | Heterocyclic compounds | CBR3, BRIX1, CCNY | MGLL 996/4885ENPP2 2496/4885ATXN2 1240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.