SCHEMBL27216583

SCHEMBL27216583

CC(C)(C)OC(=O)N1CC2(CC(n3cc(C#Cc4ccc5c(c4)CN(C4CCC(=O)NC4=O)C5=O)cn3)C2)C1

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 11/20 0.44
▸ DDB1 Q16531 2/20 0.42
▸ IKZF2 Q9UKS7 8/20 0.41
▸ CSNK1A1 P48729 3/20 0.40
▸ SALL4 Q9UJQ4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30985154 0.82 CRBN (0.45) CRBNDDB1IKZF2CSNK1A1SALL4
SCHEMBL30984814 0.81 CRBN (0.46) CRBNDDB1IKZF2CSNK1A1SALL4
SCHEMBL30080844 0.81 CRBN (0.43) CRBNIKZF2CSNK1A1
SCHEMBL24880488 0.80 CRBN (0.47) CRBNIKZF2CSNK1A1
SCHEMBL31748857 0.80 CRBN (0.53) CRBNDDB1IKZF2CSNK1A1SALL4
SCHEMBL21759799 0.80 CRBN (0.53) CRBNDDB1IKZF2CSNK1A1SALL4
SCHEMBL20235032 0.79 CRBN (0.49) CRBNDDB1IKZF2CSNK1A1SALL4
SCHEMBL30906267 0.79 CRBN (0.52) CRBNDDB1IKZF2CSNK1A1SALL4
SCHEMBL20231475 0.79 CRBN (0.52) CRBNDDB1IKZF2CSNK1A1SALL4
SCHEMBL30080867 0.78 CRBN (0.42) CRBNDDB1IKZF2CSNK1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240383908-A1 SYNTHESIS AND APPLICATION OF PHOSPHATASE DEGRADER HINOVA PHARMACEUTICALS INC. (CN) 2024-11-21 — — US disclosed
CN-115594666-B Synthesis and application of phosphatase degradation agent 海创药业股份有限公司 2024-05-31 — — CN disclosed
EP-4368614-A1 SYNTHESIS AND APPLICATION OF PHOSPHATASE DEGRADER Hinova Pharmaceuticals Inc. (CN) 2024-05-15 — — EP disclosed
CN-115594666-A Synthesis and application of phosphatase degrading agent 海创药业股份有限公司(CN) 2023-01-13 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240383908-A1 SYNTHESIS AND APPLICATION OF PHOSPHATASE DEGRADER DUSP1, PPM1D, PTPN1 CRBN 576/4885DDB1 1687/4885IKZF2 1349/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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