Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 8/20 | 0.43 |
| ▸ | IKZF2 | Q9UKS7 | 10/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27216583 | 0.81 | CRBN (0.44) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL24880488 | 0.79 | CRBN (0.47) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL30080888 | 0.79 | CRBN (0.41) | CRBNIKZF2CSNK1A1CHRM2CHRM4 | |
| SCHEMBL27216565 | 0.76 | CRBN (0.39) | CRBNIKZF2CSNK1A1IKZF1 | |
| SCHEMBL23226003 | 0.71 | CRBN (0.56) | CRBNIKZF2CSNK1A1IKZF1 | |
| SCHEMBL29439947 | 0.70 | CRBN (0.57) | CRBNIKZF2CSNK1A1IKZF1 | |
| SCHEMBL22512063 | 0.70 | CRBN (0.57) | CRBNIKZF2CSNK1A1IKZF1 | |
| SCHEMBL30241725 | 0.70 | CRBN (0.61) | CRBNIKZF2CSNK1A1 | |
| SCHEMBL31722341 | 0.70 | CRBN (0.58) | CRBNIKZF2CSNK1A1IKZF1 | |
| SCHEMBL21759818 | 0.69 | CRBN (0.65) | CRBNIKZF2CSNK1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594666-B | Synthesis and application of phosphatase degradation agent | 海创药业股份有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-115594666-A | Synthesis and application of phosphatase degrading agent | 海创药业股份有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |