SCHEMBL27217166

SCHEMBL27217166

Cn1ccnc1C1CCC1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CCNE1 P24864 2/20 0.41
CDK2 P24941 2/20 0.41
LPO P22079 1/20 0.40
F10 P00742 1/20 0.36
KCNH2 Q12809 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TNK2 Q07912 6/20 0.35
FGFR2 P21802 1/20 0.34
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
KMT2A Q03164 1/20 0.33
FGFR1 P11362 1/20 0.33
IGF1R P08069 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12903263 0.94 CCNE1 (0.46) CCNE1CDK2LPOF10L3MBTL1
SCHEMBL3532209 0.91
SCHEMBL19090065 0.86 CCNE1 (0.35) CCNE1CDK2LPOF10L3MBTL1
SCHEMBL19090066 0.86 CCNE1 (0.35) CCNE1CDK2LPOF10L3MBTL1
SCHEMBL1008868 0.86 CCNE1 (0.35) CCNE1CDK2LPOF10L3MBTL1
SCHEMBL27217132 0.84 LPO (0.38) CCNE1CDK2LPOF10KCNH2
SCHEMBL15431994 0.84 F10 (0.40) CCNE1CDK2LPOF10MEN1
SCHEMBL27217134 0.84 LPO (0.38) CCNE1CDK2LPOF10KCNH2
SCHEMBL15942427 0.82 MEN1 (0.42) LPOF10TNK2MEN1KMT2A
SCHEMBL14960627 0.82 ALDH1A1 (0.41) LPOF10TNK2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4584259-A1 CK1ALPHA AND DUAL CK1ALPHA / GSPT1 DEGRADING COMPOUNDS Innovo Therapeutics, Inc. (US) 2025-07-16 EP disclosed
US-20240158370-A1 CK1 alpha AND DUAL CK1 alpha / GSPT1 DEGRADING COMPOUNDS INNOVO THERAPEUTICS, INC. 2024-05-16 US disclosed
WO-2024054832-A1 CK1α AND DUAL CK1α / GSPT1 DEGRADING COMPOUNDS INNOVO THERAPEUTICS, INC. (US) 2024-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240158370-A1 CK1 alpha AND DUAL CK1 alpha / GSPT1 DEGRADING COMPOUNDS CKS1B, CKS2, MARK1 CCNE1 285/4885CDK2 189/4885LPO 4602/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.