SCHEMBL27217239

SCHEMBL27217239

Cn1nc(I)cc1C1CCC(F)(F)CC1

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.39
PDE2A O00408 1/20 0.37
PSMB8 P28062 1/20 0.30
PSMB9 P28065 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15882679 0.77 PLAT (0.39)
SCHEMBL15890034 0.73 CHRNB2 (0.36)
SCHEMBL17407482 0.72 PSMB8 (0.34) PSMB8PSMB9
SCHEMBL19723887 0.70 HDAC4 (0.43) KDM1APDE2A
SCHEMBL15890082 0.70 MAP3K12 (0.47)
SCHEMBL17387977 0.67 MAP3K12 (0.44) PSMB8PSMB9
SCHEMBL15882677 0.66 MAP3K12 (0.43)
SCHEMBL15890099 0.65 THRB (0.51)
SCHEMBL18685697 0.65 PSMB8 (0.30) PSMB8PSMB9
SCHEMBL17388028 0.64 MAP3K12 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4584259-A1 CK1ALPHA AND DUAL CK1ALPHA / GSPT1 DEGRADING COMPOUNDS Innovo Therapeutics, Inc. (US) 2025-07-16 EP disclosed
US-20240158370-A1 CK1 alpha AND DUAL CK1 alpha / GSPT1 DEGRADING COMPOUNDS INNOVO THERAPEUTICS, INC. 2024-05-16 US disclosed
WO-2024054832-A1 CK1α AND DUAL CK1α / GSPT1 DEGRADING COMPOUNDS INNOVO THERAPEUTICS, INC. (US) 2024-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240158370-A1 CK1 alpha AND DUAL CK1 alpha / GSPT1 DEGRADING COMPOUNDS CKS1B, CKS2, MARK1 KDM1A 69/4885PDE2A 2904/4885PSMB8 672/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.