Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | TEK | Q02763 | 1/20 | 0.34 |
| ▸ | VCP | P55072 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30813645 | 0.95 | SSTR4 (0.35) | SSTR4LCKSRCTEKVCP | |
| SCHEMBL27217986 | 0.83 | LCK (0.35) | LCKSRCTEKVCPPDPK1 | |
| SCHEMBL27217794 | 0.81 | USP30 (0.37) | LCKSRCTEK | |
| SCHEMBL27217996 | 0.78 | FLT3 (0.34) | — | |
| SCHEMBL30813372 | 0.77 | LCK (0.35) | SSTR4LCKSRCTEKVCP | |
| SCHEMBL27217810 | 0.77 | SRC (0.36) | LCKSRCTEK | |
| SCHEMBL27217958 | 0.76 | VCP (0.31) | VCP | |
| SCHEMBL30813409 | 0.75 | USP30 (0.39) | PDPK1 | |
| SCHEMBL27088011 | 0.75 | RET (0.33) | VCPPDPK1 | |
| SCHEMBL20692747 | 0.73 | SRC (0.39) | SRCPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240158394-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. | 2024-05-16 | — | — | US | disclosed |
| WO-2024059200-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2024-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240158394-A1 | NEK7 INHIBITORS | NEK7, NEK5, NEK1 | SSTR4 4781/4885LCK 3171/4885SRC 1597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.