Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 8/20 | 0.74 |
| ▸ | FGFR2 | P21802 | 8/20 | 0.74 |
| ▸ | FGFR4 | P22455 | 8/20 | 0.74 |
| ▸ | FGFR3 | P22607 | 8/20 | 0.74 |
| ▸ | SRC | P12931 | 5/20 | 0.74 |
| ▸ | PPARG | P37231 | 5/20 | 0.58 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL144476 | 0.97 | FGFR1 (0.74) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL147746 | 0.97 | FGFR1 (0.74) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL143675 | 0.86 | FGFR1 (1.00) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL3576647 | 0.84 | PPARG (0.76) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL3578768 | 0.84 | FGFR1 (0.74) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL147378 | 0.83 | FGFR1 (0.72) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL146452 | 0.83 | FGFR1 (0.72) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL4656306 | 0.81 | FGFR1 (0.68) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL17969780 | 0.80 | FGFR1 (0.88) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL17969773 | 0.80 | FGFR1 (0.49) | FGFR1FGFR2FGFR4FGFR3SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240156825-A1 | USE OF SELECTIVE VEGFR2 AND FGFR1 INHIBITORS | FOUNTAIN THERAPEUTICS INC (US) | 2024-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240156825-A1 | USE OF SELECTIVE VEGFR2 AND FGFR1 INHIBITORS | FGFR1, FRS2, FGFR2 | FGFR1 1/4885FGFR2 3/4885FGFR4 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.