Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 8/20 | 0.68 |
| ▸ | FGFR2 | P21802 | 8/20 | 0.68 |
| ▸ | FGFR4 | P22455 | 8/20 | 0.68 |
| ▸ | FGFR3 | P22607 | 8/20 | 0.68 |
| ▸ | SRC | P12931 | 5/20 | 0.68 |
| ▸ | ESR1 | P03372 | 6/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.55 |
| ▸ | PPARG | P37231 | 4/20 | 0.54 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3578768 | 0.96 | FGFR1 (0.74) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL3575957 | 0.89 | FGFR1 (0.70) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL4655931 | 0.88 | PPARG (0.71) | FGFR1FGFR2FGFR4FGFR3SRC | |
| Isopropylamine SCHEMBL3581231 | 0.84 | FGFR1 (0.63) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL144476 | 0.83 | FGFR1 (0.74) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL3570952 | 0.82 | PPARG (0.74) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL143675 | 0.82 | FGFR1 (1.00) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL146452 | 0.82 | FGFR1 (0.72) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL27218306 | 0.81 | FGFR1 (0.74) | FGFR1FGFR2FGFR4FGFR3SRC | |
| SCHEMBL4658483 | 0.79 | PPARG (0.73) | FGFR1FGFR2FGFR4FGFR3SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756036-A4 | INDENE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2008-04-16 | — | — | EP | disclosed |
| EP-1756036-A1 | INDENE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Korea Research Institute of Chemical Technology (KR) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005100297-A1 | INDENE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2005-10-27 | — | — | WO | disclosed |