Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.58 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11550295 | 0.84 | FFAR1 (0.64) | FFAR1APPMAPTCA12CA1 | |
| SCHEMBL11548470 | 0.81 | FFAR1 (0.61) | FFAR1APPMAPTMEN1KMT2A | |
| Diphenylacetylene SCHEMBL15666790 | 0.79 | APP (0.67) | FFAR1APPMAPTGRM5MEN1 | |
| SCHEMBL5966228 | 0.78 | — | — | |
| SCHEMBL2341 | 0.78 | — | — | |
| SCHEMBL2340 | 0.78 | — | — | |
| SCHEMBL2430307 | 0.77 | ALDH1A1 (0.59) | FFAR1APPMAPTCA12CA1 | |
| SCHEMBL18334296 | 0.77 | MAPT (0.75) | FFAR1APPMAPTCA12CA1 | |
| SCHEMBL23630615 | 0.76 | MAOB (0.55) | MAPTCA1ALDH1A1CYP1A2CYP2C9 | |
| Water SCHEMBL28448011 | 0.76 | MAOB (0.55) | MAPTCA1ALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3908587-B1 | METHOD FOR SYNTHESIS OF DIAZABICYCLO[6.2.0]DECANE RELATED COMPOUNDS | EISAI R&D MAN CO LTD (JP) | 2024-05-22 | — | — | EP | disclosed |
| CN-113661166-A | Process for the synthesis of diazabicyclo [6.2.0] decane-related compounds | 卫材R&D管理有限公司 | 2021-11-16 | — | — | CN | disclosed |