Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | DGKA | P23743 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2722240 | 0.94 | CHRM5 (0.41) | CHRM5CHRM3KDM4ELMNADUSP3 | |
| SCHEMBL29808366 | 0.79 | CHRM5 (0.39) | CHRM5CHRM3HSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL31365998 | 0.78 | SIGMAR1 (0.43) | CHRM5CHRM3KDM4EHSD17B10SIGMAR1 | |
| SCHEMBL29589277 | 0.77 | CHRM5 (0.36) | CHRM5CHRM3HSD17B10SMN1; SMN2SIGMAR1 | |
| SCHEMBL29299554 | 0.76 | CHRM5 (0.50) | CHRM5CHRM3HSD17B10SIGMAR1 | |
| SCHEMBL472213 | 0.76 | CHRM5 (0.50) | CHRM5CHRM3HSD17B10SIGMAR1 | |
| SCHEMBL306395 | 0.76 | CHRM5 (0.50) | CHRM5CHRM3HSD17B10SIGMAR1 | |
| SCHEMBL20179968 | 0.76 | CHRM5 (0.50) | CHRM5CHRM3LMNAMEN1KMT2A | |
| SCHEMBL21695211 | 0.76 | CHRM5 (0.50) | CHRM5CHRM3LMNAMEN1KMT2A | |
| SCHEMBL8038178 | 0.75 | CHRM5 (0.48) | CHRM5CHRM3HSD17B10SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2635311-A1 | CEST SYSTEMS EXHIBITING A CONCENTRATION INDEPENDENT RESPONSIVENESS | Bracco Imaging S.p.A (IT) | 2013-09-11 | — | — | EP | disclosed |
| WO-2012059576-A1 | CEST SYSTEMS EXHIBITING A CONCENTRATION INDEPENDENT RESPONSIVENESS | BRACCO IMAGING SPA (IT) | 2012-05-10 | — | — | WO | disclosed |