Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 4/20 | 0.38 |
| ▸ | DHODH | Q02127 | 11/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ASPH | Q12797 | 2/20 | 0.35 |
| ▸ | RIOX2 | Q8IUF8 | 2/20 | 0.35 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.35 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30866576 | 0.90 | DHODH (0.37) | MAP2K1DHODHKDM4EASPHRIOX2 | |
| SCHEMBL23673873 | 0.89 | MAP2K1 (0.35) | MAP2K1DHODHKDM4EMAP2K2NUDT1 | |
| SCHEMBL27224638 | 0.81 | DHODH (0.37) | MAP2K1DHODHKDM4EASPHRIOX2 | |
| SCHEMBL27224625 | 0.80 | NUDT1 (0.34) | MAP2K1DHODHKDM4EASPHRIOX2 | |
| SCHEMBL30459905 | 0.79 | MAP2K1 (0.35) | MAP2K1DHODHKDM4EMAP2K2NUDT1 | |
| SCHEMBL23673990 | 0.79 | MAP2K1 (0.35) | MAP2K1DHODHKDM4EMAP2K2NUDT1 | |
| SCHEMBL23673984 | 0.76 | KDM4E (0.43) | MAP2K1DHODHKDM4EASPHRIOX2 | |
| SCHEMBL29425395 | 0.76 | KDM4E (0.43) | MAP2K1DHODHKDM4EASPHRIOX2 | |
| SCHEMBL24849669 | 0.73 | DHODH (0.36) | MAP2K1DHODHKDM4ENUDT1 | |
| SCHEMBL23673877 | 0.72 | MAP2K1 (0.37) | MAP2K1DHODHKDM4EMAP2K2NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4375273-A1 | METHOD FOR PRODUCING ARYLAMIDE DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-05-29 | — | — | EP | disclosed |