Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.35 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16845644 | 0.95 | TRPA1 (0.44) | TRPA1TRPM8TRPV1ROCK2ROCK1 | |
| SCHEMBL16845737 | 0.82 | IRAK4 (0.51) | TRPA1TRPM8L3MBTL1IRAK4MEN1 | |
| SCHEMBL16845710 | 0.81 | ROCK1 (0.47) | TRPA1ROCK2ROCK1RXFP1L3MBTL1 | |
| SCHEMBL16845708 | 0.80 | L3MBTL1 (0.57) | ROCK2ROCK1L3MBTL1RPS6KB1RPS6KA1 | |
| SCHEMBL16834643 | 0.79 | TRPA1 (0.48) | TRPA1TRPM8TRPV1ROCK2ROCK1 | |
| SCHEMBL16845739 | 0.79 | L3MBTL1 (0.43) | ROCK2ROCK1L3MBTL1IRAK4RPS6KB1 | |
| SCHEMBL16845744 | 0.79 | MKNK1 (0.52) | TRPA1ROCK2ROCK1L3MBTL1IRAK4 | |
| SCHEMBL680404 | 0.78 | ROCK1 (0.36) | ROCK2ROCK1L3MBTL1RPS6KB1RPS6KA1 | |
| SCHEMBL16845713 | 0.78 | AXL (0.43) | ROCK2ROCK1L3MBTL1IRAK4RPS6KB1 | |
| SCHEMBL22176838 | 0.77 | L3MBTL1 (0.41) | ROCK2ROCK1L3MBTL1IRAK4RPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240174647-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | NEURON23, INC. | 2024-05-30 | — | — | US | disclosed |
| WO-2024073073-A2 | KINASE MODULATORS AND METHODS OF USE THEREOF | NEURON23, INC. (US) | 2024-04-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240174647-A1 | KINASE MODULATORS AND METHODS OF USE THEREOF | LRRK2, MAP3K20, MAP3K5 | TRPA1 3194/4885TRPM8 2457/4885TRPV1 3561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.