Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1247747 | 0.80 | MAPK1 (0.42) | CYP1A2TSHRMAPTALDH1A1NPC1 | |
| SCHEMBL5642066 | 0.79 | CYP1A2 (0.64) | CYP1A2TSHRMAPTALDH1A1LMNA | |
| SCHEMBL13197220 | 0.77 | CYP1A2 (0.56) | CYP1A2TSHRMAPTALDH1A1LMNA | |
| SCHEMBL29524945 | 0.77 | CYP1A2 (0.56) | CYP1A2TSHRMAPTALDH1A1LMNA | |
| SCHEMBL1645260 | 0.73 | CYP1A2 (0.56) | CYP1A2TSHRMAPTALDH1A1LMNA | |
| SCHEMBL131459 | 0.72 | CYP1A2 (0.51) | CYP1A2TSHRMAPTALDH1A1LMNA | |
| SCHEMBL127485 | 0.72 | CYP1A2 (0.61) | CYP1A2TSHRMAPTALDH1A1LMNA | |
| SCHEMBL5169193 | 0.71 | CYP1A2 (0.55) | CYP1A2TSHRMAPTALDH1A1LMNA | |
| SCHEMBL23529953 | 0.71 | CYP1A2 (0.50) | CYP1A2TSHRMAPTALDH1A1LMNA | |
| SCHEMBL29549951 | 0.71 | CYP1A2 (0.50) | CYP1A2TSHRMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240174672-A1 | Spirocycle Containing Pyridone Compounds | PROTEGO BIOPHARMA, INC. | 2024-05-30 | — | — | US | claimed |
| WO-2024092037-A1 | SPIROCYCLE CONTAINING PYRIDONE COMPOUNDS | PROTEGO BIOPHARMA, INC. (US) | 2024-05-02 | — | — | WO | claimed |
| US-20240174672-A1 | Spirocycle Containing Pyridone Compounds | PROTEGO BIOPHARMA, INC. | 2024-05-30 | — | — | US | disclosed |
| WO-2024092037-A1 | SPIROCYCLE CONTAINING PYRIDONE COMPOUNDS | PROTEGO BIOPHARMA, INC. (US) | 2024-05-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240174672-A1 | Spirocycle Containing Pyridone Compounds | TTR, BCL6, PLPBP | CYP1A2 2090/4885TSHR 3699/4885MAPT 100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.